Evidence map›Paper›PMID 24287713›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2014

Diagnostic performance of low-dose rest/stress Tc-99m tetrofosmin myocardial perfusion SPECT using the 530c CZT camera: quantitative vs visual analysis.

Fabio P Esteves, James R Galt, Russell D Folks, Liudmila Verdes, Ernest V Garcia

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 46 citations in OpenAlex.

  1. Deep learning prediction of quantitative coronary angiography values using myocardial perfusion images with a CZT camera.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  2. Article
  3. Review
  4. Quantitative analysis: Specific normal database for the best practice.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  5. Diagnostic performance of an artificial intelligence-driven cardiac-structured reporting system for myocardial perfusion SPECT imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  6. Effect of reduced photon count levels and choice of normal data on semi-automated image assessment in cardiac SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  7. Myocardial perfusion imaging in overweight patients and women: Is it CZT good enough?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  8. Article
  9. Diagnostic implications of CZT SPECT and impact of CT attenuation correction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  10. Contemporary Cardiac SPECT Imaging-Innovations and Best Practices: An Information Statement from the American Society of Nuclear Cardiology.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  11. New techniques, distinctive population, unique normal databases.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  12. Myocardial perfusion imaging: Lessons learned and work to be done-update.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Nuclear cardiology as it should look in the twenty-first century.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  19. Article
  20. Angina and mental stress-induced myocardial ischemia.Journal of psychosomatic research · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fabio P EstevesDepartment of Radiology, Emory University School of Medicine, 1364 Clifton Road, NE, Atlanta, GA, 30322, USA, festeve@emory.edu.
James R Galt
Russell D Folks
Liudmila Verdes
Ernest V Garcia
Emory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe set out to develop normal databases and prospectively validate abnormality criteria for a low-dose Tc-99m tetrofosmin myocardial perfusion SPECT protocol using the 530c CZT camera.

methodsAll patients received 6 mCi rest/20 mCi stress doses of Tc-99m tetrofosmin. Rest and stress images were obtained over 7-9 and 5-7 minutes according to the chest size. Low-dose CT of the chest was obtained on a standalone CT scanner. Forty patients with very low likelihood (LLK) of coronary artery disease (CAD) were used to define the normal count distributions. The abnormality criteria were prospectively validated in 55 patients who had coronary angiography and in 40 patients with LLK of CAD.

resultsThe results for quantitative non-attenuation-corrected (AC) and AC analysis and visual analysis were as follows: sensitivity of 79%, 85%, and 92% (P = NS) and specificity of 44%, 75%, and 56% (P = NS), respectively. The normalcy rates for quantitative non-AC and AC analyses and visual analysis were 95%, 98%, and 98% (P = NS).

conclusionsWe have developed non-AC and AC normal databases for low-dose rest/stress Tc-99m tetrofosmin myocardial perfusion SPECT protocol using the 530c CZT camera. The per-patient diagnostic performance of quantitative analyses is not significantly different from visual analysis by an experienced reader.

Indexed as

Organophosphorus CompoundsOrganotechnetium CompoundsAgedCoronary AngiographyCoronary Artery DiseaseExercise TestFemaleHumansMaleMiddle AgedMyocardial IschemiaMyocardial Perfusion ImagingProspective StudiesRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificityOrganophosphorus CompoundsOrganotechnetium CompoundsRadiopharmaceuticalstechnetium tc-99m tetrofosmin

Identifiers

PMID24287713
OpenAlexW2060896307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.