Evidence map›Paper›PMID 24287619›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2013

Anterior cruciate ligament elasticity and force for flexion during the menstrual cycle.

Haneul Lee, Jerrold S Petrofsky, Noha Daher, Lee Berk, Michale Laymon, Iman Akef Khowailed

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Menstrual Cycle and Sport Injuries: A Systematic Review.International journal of environmental research and public health · 2023
    Pooled it
  2. Article
  3. Anterior cruciate ligament injury incidence in male and female soccer players: A longitudinal study over six consecutive seasons.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Article
  4. Article
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  7. Anatomical Tissue Engineering of the Anterior Cruciate Ligament Entheses.International journal of molecular sciences · 2023
    Review
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  18. Tamoxifen Inhibits the Progression of Trauma-Induced Heterotopic Ossification in Mice.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  19. Preoperative laxity in ACL-deficient knees increases with posterior tibial slope and medial meniscal tears.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Haneul LeeDepartment of Physical Therapy, School of Allied Health Professions, Loma Linda University, Loma Linda, USA.
Jerrold S Petrofsky
Noha Daher
Lee Berk
Michale Laymon
Iman Akef Khowailed
Loma Linda University · USTouro University Nevada · USUniversity of Cambodia · KH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA high occurrence of knee injuries have been observed in women during the menstrual cycle (MC). As a result, numerous studies have been conducted regarding knee ligament elasticity during the MC. Some researchers believe that since estrogen receptor b exists in ligaments and tendons in the knee, estrogen may modulate towards a state of laxity. However, increased tissue temperature also observed during the MC can predispose ligament and tendon laxness. Therefore, the purpose of this study was to assess in women the relationship between Estradiol (E2) serum concentrations and tissue temperature during the MC and their combined effect on knee laxity. MATERIAL AND

methodsTen non-athletic young healthy females, 18 to 30 years of age participated in the study. E2 serum concentrations, anterior cruciate ligament (ACL) elasticity, and force to flex the knee (FFK), knee flexion-extension hysteresis (KFEH) were assessed both at ambient temperature (22 °C) and after 38 °C warming. Testing was performed multiple times during the participant's MC, for one full MC.

resultsACL elasticity was significantly higher (P<0.01) and FFK and KFEH were significantly lower (p<0.05) during ovulation when E2 levels were highest. ACL elasticity was still higher during ovulation after warming to 38 °C. But, the effects of MC on FFK and KFEH were reduced by tissue warming.

conclusionsACL elasticity, FFK, and KFEH was affected not only by E2 but also tissue temperature. However, E2 had more impact on ACL elasticity while tissue temperature had more impact on FFK and KFEH at 38 °C warming.

Indexed as

Body TemperatureAdultAnalysis of VarianceAnterior Cruciate LigamentBiomechanical PhenomenaElasticityEstradiolFemaleHumansJoint InstabilityMenstrual CycleRange of Motion, ArticularEstradiol

Identifiers

PMID24287619
PMCPMC3862144
OpenAlexW2069443058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.