ArticleViruses2013
First isolation of a giant virus from wild Hirudo medicinalis leech: Mimiviridae isolation in Hirudo medicinalis.
Article in Viruses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Leech Diversity in the Maghreb (North Africa): A Checklist and a Case Report of Parasitism on a Berber Toad (Biology · 2026Article
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- Shrinking of repeating unit length in leucine-rich repeats from double-stranded DNA viruses.Archives of virology · 2021Article
- A Comprehensive Review of Medicinal Leeches in Plastic and Reconstructive Surgery.Plastic and reconstructive surgery. Global open · 2019Article
- Review
- High-throughput isolation of giant viruses using high-content screening.Communications biology · 2019Article
- A comparative review of viral entry and attachment during large and giant dsDNA virus infections.Archives of virology · 2017Review
- Mimivirus: leading the way in the discovery of giant viruses of amoebae.Nature reviews. Microbiology · 2017Review
- Genome Characterization of the First Mimiviruses of Lineage C Isolated in Brazil.Frontiers in microbiology · 2017Article
- Amoebae, Giant Viruses, and Virophages Make Up a Complex, Multilayered Threesome.Frontiers in cellular and infection microbiology · 2017Review
- Giant Viruses of Amoebas: An Update.Frontiers in microbiology · 2016Review
- Mimivirus Fibrils Are Important for Viral Attachment to the Microbial World by a Diverse Glycoside Interaction Repertoire.Journal of virology · 2015Article
- Article
- Isolation of new Brazilian giant viruses from environmental samples using a panel of protozoa.Frontiers in microbiology · 2015Article
- Faustovirus-Like Asfarvirus in Hematophagous Biting Midges and Their Vertebrate Hosts.Frontiers in microbiology · 2015Article
- Genomic comparison of closely related Giant Viruses supports an accordion-like model of evolution.Frontiers in microbiology · 2015Article
- Acanthamoeba polyphaga mimivirus and other giant viruses: an open field to outstanding discoveries.Virology journal · 2014Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Giant viruses and amoebae are common in freshwater, where they can coexist with other living multicellular organisms. We screened leeches from the species Hirudo medicinalis for giant viruses. We analyzed five H. medicinalis obtained from Tunisia (3) and France (2). The leeches were decontaminated and then dissected to remove internal parts for co-culture with Acanthamoeba polyphaga. The genomes of isolated viruses were sequenced on a 454 Roche instrument, and a comparative genomics analysis was performed. One Mimivirus was isolated and the strain was named Hirudovirus. The genome assembly generated two scaffolds, which were 1,155,382 and 25,660 base pairs in length. Functional annotations were identified for 47% of the genes, which corresponds to 466 proteins. The presence of Mimividae in the same ecological niche as wild Hirudo may explain the presence of the mimivirus in the digestive tract of the leech, and several studies have already shown that viruses can persist in the digestive tracts of leeches fed contaminated blood. As leeches can be used medically and Mimiviruses have the potential to be an infectious agent in humans, patients treated with leeches should be surveyed to investigate a possible connection.
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