ArticleToxins2013
Impact of pH on the stability and the cross-reactivity of ochratoxin A and citrinin.
Article in Toxins, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 43 citations in OpenAlex.
- Study on the effect of ascorbic acid on the biosynthesis of pigment and citrinin in red yeast rice based on comparative transcriptomics.Frontiers in microbiology · 2024Article
- Root uptake and metabolization of Alternaria toxins by winter wheat plants using a hydroponic system.Mycotoxin research · 2023Article
- Review
- Molecular Docking and In Vitro Studies of Ochratoxin A (OTA) Biodetoxification Testing Three Endopeptidases.Molecules (Basel, Switzerland) · 2023Article
- Minimizing Ochratoxin A Contamination through the Use of Actinobacteria and Their Active Molecules.Toxins · 2020Article
- Assessment of Ochratoxin A Exposure in Ornamental and Self-Consumption Backyard Chickens.Veterinary sciences · 2020Article
- Article
- Effect of initial pH, different nitrogen sources, and cultivation time on the production of yellow or orangeFood science & nutrition · 2019Article
- In vitro adsorption of aflatoxin BMycotoxin research · 2019Article
- Coordination of mycotoxins with lanthanides in luminescent complexes.Mycotoxin research · 2019Article
- Comprehensive study on the degradation of ochratoxin A in water by spectroscopic techniques and DFT calculations.RSC advances · 2019Article
- In vitro selection of an XNA aptamer capable of small-molecule recognition.Nucleic acids research · 2018Article
- Ochratoxin A: 50 Years of Research.Toxins · 2016Review
- Recent Advances for the Detection of Ochratoxin A.Toxins · 2015Review
- In vitro exposure of Penicillium mycotoxins with or without a modified yeast cell wall extract (mYCW) on bovine macrophages (BoMacs).Mycotoxin research · 2015Article
- Saccharomyces cerevisiae cell wall components as tools for ochratoxin a decontamination.Toxins · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycotoxins are secondary metabolites produced by several fungi contaminating crops. In several countries, the maximum permitted levels of mycotoxins are found in foodstuffs and feedstuffs. The common strategy of mycotoxin analysis involves extraction, clean-up and quantification by chromatography. In this paper, we analyzed the reasons of underestimation of ochratoxin A (OTA) content in wine, and overestimation of OTA in wheat, depending on the pH of the clean-up step and the simultaneous presence of citrinin (CIT). We demonstrated that the increase of pH by adding polyethylene glycol (PEG) to wine led to an underestimation of OTA by conversion of OTA into open ring ochratoxin A OP-OA. In comparing three methods of extraction and clean-up for the determination of OTA and CIT in wheat--(i) an inter-laboratory validated method for OTA in cereals using immunoaffinity column clean-up (IAC) and extraction by acetonitrile/water; (ii) a validated method using IAC and extraction with 1% bicarbonate Na; and (iii) an in-house validated method based on acid liquid/liquid extraction--we observed an overestimation of OTA after immunoaffinity clean-up when CIT is also present in the sample, whereas an underestimation was observed when OTA was alone. Under neutral and alkaline conditions, CIT was partially recognized by OTA antibodies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.