Evidence map›Paper›PMID 24287470›Full record

ArticleAmerican journal of epidemiology2014

Invited commentary: composite outcomes as an attempt to escape from selection bias and related paradoxes.

Miguel A Hernán, Enrique F Schisterman, Sonia Hernández-Díaz

Abstract readComment
In one paragraph

Article in American journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. The association of maternal country/region of origin and nativity with infant mortality rate among Hispanic preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  5. Article
  6. Observational
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. No Right Answers without Knowing Your Question.Paediatric and perinatal epidemiology · 2016
    Article
  15. Article
  16. Maternal obesity and development of the preterm newborn at 2 years.Acta paediatrica (Oslo, Norway : 1992) · 2015
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Miguel A Hernán
Enrique F Schisterman
Sonia Hernández-Díaz

Funding

Estimating Effects of Interventions in Longitudinal DataR01HL080644 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI HERNAN, MIGUEL · 2005 to 2013
$4.0M
Dynamic strategies for the clinical management of HIV diseaseR01AI102634 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI HERNAN, MIGUEL · 2013 to 2017
$2.6M
ROC Curve MethodologyZIAHD008761 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SCHISTERMAN, ENRIQUE F. · 2009 to 2021
$2.1M
Intramural NIH HHSNHLBI NIH HHS R01 HL080644NIAID NIH HHS R01 AI102634
6 · The paper itself

Abstract

This commentary reviews the recent history of explanations to crossover paradoxes such as the birth weight and gestational age paradoxes, with a special emphasis on the current proposal by Kramer et al. in this issue of the Journal (Am J Epidemiol. 2014;179(3):361-367). We contend that the causal structure of these paradoxes is essentially identical to that of several well-known selection biases. We then consider the pros and cons of using composite outcomes to circumvent these selection biases.

Indexed as

Data Interpretation, StatisticalEpidemiologic Research DesignGestational AgePerinatal MortalityStillbirthFemaleHumansPregnancyPremature Birthcausal diagramscomposite outcomesparadoxselection bias

Identifiers

PMID24287470
PMCPMC3895101

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.