ReviewTrends in neurosciences2014
Measuring and using light in the melanopsin age.
Review in Trends in neurosciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 389 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
389 citing papers in PubMed, 4 syntheses or guidelines pooled it, 1,206 citations in OpenAlex.
- Bright light therapy for post-stroke sleep disturbances: a systematic review and meta-analysis.Frontiers in neurology · 2026Pooled it
- A systematic review and meta-analysis on light therapy for sleep disorders in shift workers.Scientific reports · 2025Pooled it
- Circadian light therapy and light dose for depressed young people: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Lighting in the Home and Health: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- The Effect of Light Intensity and the Timing of Light Exposure on Choroidal Thickness.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Trial
- Different light color temperatures in the morning on the effectiveness of rehabilitation training in patients with ischemic stroke: a prospective, single-center, randomized controlled clinical trial.Journal of neuroengineering and rehabilitation · 2025Trial
- Trial
- Diurnal rhythms of urine volume and electrolyte excretion in healthy young men under differing intensities of daytime light exposure.Scientific reports · 2021Trial
- The effects of dynamic daylight-like light on the rhythm, cognition, and mood of irregular shift workers in closed environment.Scientific reports · 2021Trial
- Ambient bright light treatment improved proxy-rated sleep but not sleep measured by actigraphy in nursing home patients with dementia: a placebo-controlled randomised trial.BMC geriatrics · 2021Trial
- Trial
- Constructing melanopic light exposure profiles from sparse daily-route measurements.Npj biological timing and sleep · 2026Article
- Using light to establish habits in laboratory mice.Journal of behavioral addictions · 2026Article
- Considerations and guidelines for photic measurement in field studies of the physiological effects of light.Npj biological timing and sleep · 2026Review
- Divergence of Melanopsin's Intrinsic Properties and Downstream Actions.bioRxiv : the preprint server for biology · 2026Article
- Prevention of myopia in a near-primate by supplemental indigo light suggests a hypothesis for the myopia boom.Cell reports. Medicine · 2026Article
- Daylight, Daily Rhythms, and Downstream Physiology: A Translational Study in Diurnal Nile Grass Rats (Journal of biological rhythms · 2026Article
- Acute Ocular Effects of Violet and Red Light Exposure in Young Adults.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- [Daylight therapy in intensive care units: a review].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Review
- Analysis of real-world eye level light exposure through spectacle lens.Npj biological timing and sleep · 2026Article
329 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 11 institutions in 3 countries.
Funding
Abstract
Light is a potent stimulus for regulating circadian, hormonal, and behavioral systems. In addition, light therapy is effective for certain affective disorders, sleep problems, and circadian rhythm disruption. These biological and behavioral effects of light are influenced by a distinct photoreceptor in the eye, melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs), in addition to conventional rods and cones. We summarize the neurophysiology of this newly described sensory pathway and consider implications for the measurement, production, and application of light. A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.