ReviewReproductive biology2013
Endocrine and local control of the primate corpus luteum.
Review in Reproductive biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Management of infertility in women with hypothalamic hypogonadotropic hypogonadism: an expert opinion.Reproductive biology and endocrinology : RB&E · 2026Review
- Novel Aspects of the Physiology of Pregnancy in Domestic Ruminants.Animals : an open access journal from MDPI · 2025Review
- Morphological and Histological Variations of the Reproductive Organs During the Annual Cycle in a Neotropical Bat: Peters' Ghost-Faced Bat Mormoops megalophylla (Chiroptera: Mormoopidae).Journal of morphology · 2025Article
- Singleton term pregnancies resulting from frozen-thawed embryo transfer in hormone replacement cycles increase the risk of aberrant placentation, including velamentous umbilical cord insertion.Archives of gynecology and obstetrics · 2025Article
- Prostaglandin F2α regulates mitochondrial dynamics and mitophagy in the bovine corpus luteum.Life science alliance · 2023Article
- Altered GnRH neuron and ovarian innervation characterize reproductive dysfunction linked to the Fragile X messenger ribonucleoprotein (Frontiers in endocrinology · 2023Article
- Mechanisms of angioregression of the corpus luteum.Frontiers in physiology · 2023Review
- Folliculogenesis in random start protocols for oocytes cryopreservation: quantitative and qualitative aspects.Reproductive sciences (Thousand Oaks, Calif.) · 2022Article
- Diverse actions of sirtuin-1 on ovulatory genes and cell death pathways in human granulosa cells.Reproductive biology and endocrinology : RB&E · 2022Article
- Spatiotemporal expression pattern of miR-205, miR-26a-5p, miR-17-5p, let-7b-5p, and their target genes during different stages of corpus luteum in Egyptian buffaloes.Journal, genetic engineering & biotechnology · 2022Article
- The Mare: A Pertinent Model for Human Assisted Reproductive Technologies?Animals : an open access journal from MDPI · 2021Review
- Neurotensin: A novel mediator of ovulation?FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- PKA and AMPK Signaling Pathways Differentially Regulate Luteal Steroidogenesis.Endocrinology · 2021Article
- Interactions of Cortisol and Prolactin with Other Selected Menstrual Cycle Hormones Affecting the Chances of Conception in Infertile Women.International journal of environmental research and public health · 2020Article
- Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy.Frontiers in physiology · 2020Article
- Mothers, Fathers, and Others: Neural Substrates of Parental Care.Trends in neurosciences · 2019Review
- Human Luteinized Granulosa Cells-A Cellular Model for the Human Corpus Luteum.Frontiers in endocrinology · 2019Review
- The liver X receptors and sterol regulatory element binding proteins alter progesterone secretion and are regulated by human chorionic gonadotropin in human luteinized granulosa cells.Molecular and cellular endocrinology · 2018Article
- Developmental Programming of Ovarian Functions and Dysfunctions.Vitamins and hormones · 2018Review
- Increased 27-hydroxycholesterol production during luteolysis may mediate the progressive decline in progesterone secretion.Molecular human reproduction · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The primate corpus luteum is a transient endocrine gland that differentiates from the ovulatory follicle midway through the ovarian (menstrual) cycle. Its formation and limited lifespan is critical for fertility, as luteal-derived progesterone is the essential steroid hormone required for embryo implantation and maintenance of intra-uterine pregnancy until the placenta develops. It is well-established that LH and the LH-like hormone, CG, are the vital luteotropic hormones during the menstrual cycle and early pregnancy, respectively. Recent advances, particularly through genome analyses and cellular studies, increased our understanding of various local factors and cellular processes associated with the development, maintenance and repression of the corpus luteum. These include paracrine or autocrine factors associated with angiogenesis (e.g., VEGF), and that mediate LH/CG actions (e.g., progesterone), or counteract luteotropic effects (i.e., local luteolysis; e.g., PGF2α). However, areas of mystery and controversy remain, particularly regarding the signals and events that initiate luteal regression in the non-fecund cycle. Novel approaches capable of gene "knockdown" or amplification", in vivo as well as in vitro, should identify novel or underappreciated gene products that are regulated by or modulate LH/CG actions to control the functional lifespan of the primate corpus luteum. Further advances in our understanding of luteal physiology will help to improve or control fertility for purposes ranging from preservation of endangered primate species to designing novel ovary-based contraceptives and treating ovarian disorders in women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.