ReviewArchives of plastic surgery2013
Stem cells in plastic surgery: a review of current clinical and translational applications.
Review in Archives of plastic surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- Efficacy and safety of porcine collagen filler for nasolabial fold correction in Asians: a prospective multicenter, 12 months follow-up study.Journal of Korean medical science · 2014Trial
- A Layered Framework for Biological Aesthetics: A Narrative Review of Regenerative Medicine in Cosmetic Science.Cureus · 2026Review
- Intralesional Adipose-Derived Stem Cells Reverse Established Dermal Fibrosis and Modulate Angiogenesis-Related Readouts in a Murine Systemic Sclerosis Model.Tissue engineering and regenerative medicine · 2026Article
- Comparative regenerative mechanisms of adipose-derived mesenchymal stem cell- and conditioned medium-loaded three-dimensional bioprinted hydrogels in chronic diabetic wounds.Regenerative biomaterials · 2026Article
- Application of multi-needle injector for delivering human adipose stem cells to combat photoaging in nude mice.Archives of dermatological research · 2025Article
- Adipose-Derived Stromal Cell-Based Therapies for Radiation-Induced Fibrosis.Advances in wound care · 2024Review
- Reconstructive Paradigms: A Problem-Solving Approach in Complex Tissue Defects.Journal of clinical medicine · 2024Review
- Human-Induced Pluripotent Stem Cells in Plastic and Reconstructive Surgery.International journal of molecular sciences · 2024Review
- Stem cells in plastic surgery and aesthetic medicine.Postepy dermatologii i alergologii · 2023Review
- Review
- Perichondrial progenitor cells promote proliferation and chondrogenesis of mature chondrocytes.Regenerative biomaterials · 2022Article
- Regenerative and stem cell-based techniques for facial rejuvenation.Experimental biology and medicine (Maywood, N.J.) · 2021Review
- 'Fat chance': a review of adipose tissue engineering and its role in plastic and reconstructive surgery.Annals of the Royal College of Surgeons of England · 2021Review
- Stem cells in end-to-side neurorrhaphy. Experimental study in rats.Acta cirurgica brasileira · 2021Article
- The Role of Adipose-Derived Stem Cells, Dermal Regenerative Templates, and Platelet-Rich Plasma in Tissue Engineering-Based Treatments of Chronic Skin Wounds.Stem cells international · 2020Review
- Comparison of the therapeutic effects of adipose‑derived and bone marrow mesenchymal stem cells on erectile dysfunction in diabetic rats.International journal of molecular medicine · 2019Article
- From liposuction to adipose-derived stem cells: indications and technique.Acta bio-medica : Atenei Parmensis · 2019Review
- Low ozone concentrations promote adipogenesis in human adipose-derived adult stem cells.European journal of histochemistry : EJH · 2018Article
- Off-label use of adipose-derived stem cells.Annals of medicine and surgery (2012) · 2017Review
- Roles of neural stem cells in the repair of peripheral nerve injury.Neural regeneration research · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStem cells are a unique cell population characterized by self-renewal and cellular differentiation capabilities. These characteristics, among other traits, make them an attractive option for regenerative treatments of tissues defects and for aesthetic procedures in plastic surgery. As research regarding the isolation, culture and behavior of stem cells has progressed, stem cells, particularly adult stem cells, have shown promising results in both translational and clinical applications.
methodsThe purpose of this review is to evaluate the applications of stem cells in the plastic surgery literature, with particular focus on the advances and limitations of current stem cell therapies. Different key areas amenable to stem cell therapy are addressed in the literature review; these include regeneration of soft tissue, bone, cartilage, and peripheral nerves, as well as wound healing and skin aging.
resultsThe reviewed studies demonstrate promising results, with favorable outcomes and minimal complications in the cited cases. In particular, adipose tissue derived stem cell (ADSC) transplants appear to provide effective treatment options for bony and soft tissue defects, and non-healing wounds. ADSCs have also been shown to be useful in aesthetic surgery.
conclusionsFurther studies involving both the basic and clinical science aspects of stem cell therapies are warranted. In particular, the mechanism of action of stem cells, their interactions with the surrounding microenvironment and their long-term fate require further elucidation. Larger randomized trials are also necessary to demonstrate the continued safety of transplanted stem cells as well as the efficacy of cellular therapies in comparison to the current standards of care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.