ArticleThe Plant cell2013
The Arabidopsis NAC transcription factor ANAC096 cooperates with bZIP-type transcription factors in dehydration and osmotic stress responses.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers, 1 of them a synthesis that pooled it.
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Who cites it
148 citing papers in PubMed, 1 synthesis or guideline pooled it, 275 citations in OpenAlex.
- Meta-analysis of drought-tolerant genotypes in Oryza sativa: A network-based approach.PloS one · 2019Pooled it
- Genome‑Wide Identification of NAC Transcription Factors in Elymus sibiricus and Functional Characterisation of EsNAC29 in Light Inhibition.Plant, cell & environment · 2026Article
- Integration of Spatiotemporal Multi-Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome-Mediated Stress Adaptation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- De Novo Functional Characterization of AcABI5 Transcription Factor and Its Role in Physiological Responses to Salt Stress inInternational journal of molecular sciences · 2026Article
- Genome-Wide Identification and Characterization of the NAC Transcription Factor Family inPlants (Basel, Switzerland) · 2026Article
- FaRIF as a key regulator of strawberry fruit ripening: deciphering its targets and interaction networks.Horticulture research · 2026Article
- Article
- The OsMADS18-OsbZIP60 module plays a critical role in influencing grain chalkiness in rice.Science China. Life sciences · 2026Article
- Genome-wide identification, classification and expression analysis of laccase family members in Solanum lycopersicum.BMC plant biology · 2026Article
- Contrasting leaf transcriptomic responses to drought and heat stress in the desert CAM speciesFrontiers in plant science · 2026Article
- Transcriptional regulation ofGM crops & food · 2025Article
- Comprehensive Identification and Abscisic Acid-Responsive Expression Profiling of NAC Transcription Factor in Triterpenoid Saponin inBiomolecules · 2025Article
- PagHB7/PagABF4-PagEPFL9 Module Regulates Stomatal Density and Drought Tolerance in Poplar.Plant biotechnology journal · 2025Article
- Transcriptional gene network involved in drought stress response: application for crop breeding in the context of climate change.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Genome-Wide Analysis of NAC Transcription Factor Gene Family inPlants (Basel, Switzerland) · 2025Article
- Abscisic acid signaling gates salt-induced responses of plant roots.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The evolution, variation, and expression patterns under development and stress responses of the NAC gene family in the barley pan-genome.Frontiers in plant science · 2025Article
- Overexpression of NAC transcription factors from Eremopyrum triticeum promoted abiotic stress tolerance.Transgenic research · 2024Article
- Drought Tolerance in Plants: Physiological and Molecular Responses.Plants (Basel, Switzerland) · 2024Review
- Isolation and functional analysis of the Larix olgensis LoNAC3 transcription factor gene.BMC plant biology · 2024Article
88 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multiple transcription factors (TFs) play essential roles in plants under abiotic stress, but how these multiple TFs cooperate in abiotic stress responses remains largely unknown. In this study, we provide evidence that the NAC (for NAM, ATAF1/2, and CUC2) TF ANAC096 cooperates with the bZIP-type TFs ABRE binding factor and ABRE binding protein (ABF/AREB) to help plants survive under dehydration and osmotic stress conditions. ANAC096 directly interacts with ABF2 and ABF4, but not with ABF3, both in vitro and in vivo. ANAC096 and ABF2 synergistically activate RD29A transcription. Our genome-wide gene expression analysis revealed that a major proportion of abscisic acid (ABA)-responsive genes are under the transcriptional regulation of ANAC096. We found that the Arabidopsis thaliana anac096 mutant is hyposensitive to exogenous ABA and shows impaired ABA-induced stomatal closure and increased water loss under dehydration stress conditions. Furthermore, we found the anac096 abf2 abf4 triple mutant is much more sensitive to dehydration and osmotic stresses than the anac096 single mutant or the abf2 abf4 double mutant. Based on these results, we propose that ANAC096 is involved in a synergistic relationship with a subset of ABFs for the transcriptional activation of ABA-inducible genes in response to dehydration and osmotic stresses.
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