Evidence map›Paper›PMID 24285419›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2014

Insights into the mechanisms of sclerostin action in regulating bone mass accrual.

Bart O Williams

Abstract readComment
PubMed Publisher
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Anti-sclerostin antibody treatment in a rat model of progressive renal osteodystrophy.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2015
    Article
  8. Review
  9. Inhibitors of sclerostin: emerging concepts.Current opinion in rheumatology · 2014
    Review
  10. WNT signaling in bone development and homeostasis.Wiley interdisciplinary reviews. Developmental biology
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Bart O WilliamsCenter for Skeletal Disease and Tumor Metastasis, Van Andel Research Institute, Grand Rapids, MI, USA.

Funding

Analyzing the Role of Wnt Signaling in Bone DevelopmentR01AR053293 · NIAMS · VAN ANDEL RESEARCH INSTITUTE · PI WILLIAMS, BART O · 2007 to 2016
$4.0M
NIAMS NIH HHS R01 AR053293
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalAdaptor Proteins, Signal TransducingAnimalsBone and BonesGlycoproteinsIntercellular Signaling Peptides and ProteinsLow Density Lipoprotein Receptor-Related Protein-5Low Density Lipoprotein Receptor-Related Protein-6Osteogenesis ImperfectaWnt Signaling PathwayAdaptor Proteins, Signal TransducingGlycoproteinsIntercellular Signaling Peptides and ProteinsLow Density Lipoprotein Receptor-Related Protein-5Low Density Lipoprotein Receptor-Related Protein-6Lrp5 protein, mouseLrp6 protein, mouseSost protein, mouse

Identifiers

PMID24285419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.