Evidence map›Paper›PMID 24285381›Full record

ArticleAngewandte Chemie (International ed. in English)2014

Tunable visible and near-IR photoactivation of light-responsive compounds by using fluorophores as light-capturing antennas.

Thomas A Shell, Jennifer R Shell, Zachary L Rodgers, David S Lawrence

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Three-Color Protein Photolithography with Green, Red, and Far-Red Light.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Neural and behavioral control inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Article
  11. Article
  12. Light-Controlled Cell-Cycle Arrest and Apoptosis.Angewandte Chemie (International ed. in English) · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Long-wavelength photoremovable protecting groups: On the way toComputational and structural biotechnology journal · 2020
    Review
  17. Review
  18. On Command Drug Delivery via Cell-Conveyed Phototherapeutics.Small (Weinheim an der Bergstrasse, Germany) · 2019
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas A ShellDepartment of Chemistry, Division of Chemical Biology and Medicinal Chemistry, and the Department of Pharmacology, University of North Carolina,Chapel Hill, NC 27599 (USA). tshell@email.unc.edu.
Jennifer R Shell
Zachary L Rodgers
David S Lawrence

Funding

SYNTHETIC REGULATORS OF TYROSINE PROTEIN KINASESR01CA079954 · NCI · YESHIVA UNIVERSITY · PI LAWRENCE, DAVID S. · 1999 to 2016
$4.2M
NCI NIH HHS R01 CA079954NCI NIH HHS R01 CA79954
6 · The paper itself

Abstract

Although the corrin ring of vitamin B12 is unable to efficiently absorb light beyond 550 nm, it is shown that commercially available fluorophores can be used as antennas to capture long-wavelength light to promote scission of the Co-C bond at wavelengths up to 800 nm. The ability to control the molecular properties of bioactive species with long visible and near-IR light has implications for drug delivery, nanotechnology, and the spatiotemporal control of cellular behavior.

Indexed as

Infrared RaysLightAnimalsCell LineCell SurvivalDoxorubicinEnergy TransferFluorescent DyesHeLa CellsHumansMicroscopy, ConfocalPhotolysisRatsRhodaminesVitamin B 125-carboxytetramethylrhodamineDoxorubicinFluorescent DyesRhodaminesVitamin B 12cobalaminsdrug deliveryenergy transferfluorescencephotochemistry

Identifiers

PMID24285381
PMCPMC4036634

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.