Evidence map›Paper›PMID 24285306›Full record

ArticleNucleic acids research2014

PortEco: a resource for exploring bacterial biology through high-throughput data and analysis tools.

James C Hu, Gavin Sherlock, Deborah A Siegele, Suzanne A Aleksander, Catherine A Ball, Janos Demeter, Sushanth Gouni, Timothy A Holland, Peter D Karp, John E Lewis and 7 more

Erratum issuedAbstract read
In one paragraph

Article in Nucleic acids research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. The response of Escherichia coli to the alkylating agents chloroacetaldehyde and styrene oxide.Mutation research. Genetic toxicology and environmental mutagenesis · 2019
    Article
  3. Article
  4. Article
  5. Article
  6. Defining bacterial regulons using ChIP-seq.Methods (San Diego, Calif.) · 2015
    Review
  7. Databases for Microbiologists.Journal of bacteriology · 2015
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Global discovery of colonization determinants in the squid symbiont Vibrio fischeri.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  13. Article
  14. Assisted curation of regulatory interactions and growth conditions of OxyR in E. coli K-12.Database : the journal of biological databases and curation · 2014
    Article
  15. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

17 authors.

James C HuDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843, USA, Department of Genetics, Stanford University, Stanford, CA 94305, USA, Department of Biology, Texas A&M University, College Station, TX, 77843, USA, Artificial Intelligence Center, SRI International, Menlo Park, CA 94025, USA and Deptartment of Preventive Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Gavin Sherlock
Deborah A Siegele
Suzanne A Aleksander
Catherine A Ball
Janos Demeter
Sushanth Gouni
Timothy A Holland
Peter D Karp
John E Lewis
Nathan M Liles
Brenley K McIntosh
Huaiyu Mi
Anushya Muruganujan
Farrell Wymore
Paul D Thomas
Tomer Altman

Funding

EcoliHub2.0: A next-generation E. coli model organism resource (SRI Proposal ECU U24GM088849 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HU, JAMES C, SHERLOCK, GAVIN J · 2009 to 2012
$4.4M
NIGMS NIH HHS 1U24GM088849NIGMS NIH HHS U24 GM088849
6 · The paper itself

Abstract

PortEco (http://porteco.org) aims to collect, curate and provide data and analysis tools to support basic biological research in Escherichia coli (and eventually other bacterial systems). PortEco is implemented as a 'virtual' model organism database that provides a single unified interface to the user, while integrating information from a variety of sources. The main focus of PortEco is to enable broad use of the growing number of high-throughput experiments available for E. coli, and to leverage community annotation through the EcoliWiki and GONUTS systems. Currently, PortEco includes curated data from hundreds of genome-wide RNA expression studies, from high-throughput phenotyping of single-gene knockouts under hundreds of annotated conditions, from chromatin immunoprecipitation experiments for tens of different DNA-binding factors and from ribosome profiling experiments that yield insights into protein expression. Conditions have been annotated with a consistent vocabulary, and data have been consistently normalized to enable users to find, compare and interpret relevant experiments. PortEco includes tools for data analysis, including clustering, enrichment analysis and exploration via genome browsers. PortEco search and data analysis tools are extensively linked to the curated gene, metabolic pathway and regulation content at its sister site, EcoCyc.

Indexed as

Databases, GeneticAllelesDNA-Binding ProteinsEscherichia coliEscherichia coli ProteinsGenes, BacterialGenome, BacterialHigh-Throughput Nucleotide SequencingInternetPhenotypeRibosomesRNA, MessengerSoftwareDNA-Binding ProteinsEscherichia coli ProteinsRNA, Messenger

Identifiers

PMID24285306
PMCPMC3965092

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.