SynthesisThe Journal of investigative dermatology2014
The prevalence and odds of depressive symptoms and clinical depression in psoriasis patients: a systematic review and meta-analysis.
Synthesis in The Journal of investigative dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers, 10 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
165 citing papers in PubMed, 10 syntheses or guidelines pooled it, 413 citations in OpenAlex.
- Specificity of environmental risk factors for schizophrenia, bipolar disorders, and depressive disorders - umbrella review.Psychological medicine · 2025Pooled it
- Anemia in patients with hidradenitis suppurativa : A systematic review with meta-analysis.Archives of dermatological research · 2023Pooled it
- Psychosocial implications of rare genetic skin diseases affecting appearance on daily life experiences, emotional state, self-perception and quality of life in adults: a systematic review.Orphanet journal of rare diseases · 2023Pooled it
- A comprehensive overview of psoriatic research over the past 20 years: machine learning-based bibliometric analysis.Frontiers in immunology · 2023Pooled it
- Cognitive impairment in psoriasis patients: a systematic review of case-control studies.Journal of neurology · 2022Pooled it
- Prevalence and Odds of Anxiety Disorders and Anxiety Symptoms in Children and Adults with Psoriasis: Systematic Review and Meta-analysis.Acta dermato-venereologica · 2022Pooled it
- Prevalence and Odds of Signs of Depression and Anxiety in Patients with Lichen Planus: Systematic Review and Meta-analyses.Acta dermato-venereologica · 2020Pooled it
- Biologicals and small molecules in psoriasis: A systematic review of economic evaluations.PloS one · 2018Pooled it
- A systematic review and meta-analysis on Staphylococcus aureus carriage in psoriasis, acne and rosacea.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016Pooled it
- Topical treatments for scalp psoriasis.The Cochrane database of systematic reviews · 2016Pooled it
- Tofacitinib for the treatment of moderate to severe chronic plaque psoriasis in Japanese patients: Subgroup analyses from a randomized, placebo-controlled phase 3 trial.The Journal of dermatology · 2017Trial
- Apremilast, an oral phosphodiesterase 4 inhibitor, improves patient-reported outcomes in the treatment of moderate to severe psoriasis: results of two phase III randomized, controlled trials.Journal of the European Academy of Dermatology and Venereology : JEADV · 2017Trial
- Associated Factors and Quality of Life in Self-Reported Psoriasis Among Adults in Saudi Arabia: An Exploratory Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Prevalence of depression among adult psoriatic patients in Palestine: a cross-sectional study in primary healthcare settings.BMJ open · 2026Article
- Psoriasis and Psoriatic Arthritis in Pregnancy: Current Evidence and Clinical Considerations.Cureus · 2026Review
- Multi-omics profiling of chronic immune-mediated skin diseases: SKINERGY protocol and strategic evaluation.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026Observational
- Adherence to Psoriasis Remote Monitoring and Its Associations With Demographic, Clinical, and Health Care Use Characteristics: Multicenter Observational Study.JMIR formative research · 2026Observational
- Economic Impact of Timely Systemic Treatment of Psoriatic Disease in Comorbidity Risk Reduction: Literature Review and (Early) Economic Assessment.Dermatology and therapy · 2026Review
- Article
- Psychometric Evaluation of Patients with Psoriasis and their Association with Patients' Psychological Characteristics.Mediterranean journal of rheumatology · 2026Article
105 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The reported prevalence of depression in psoriasis varies substantially. This study aims to determine the prevalence and odds of depressive symptoms and clinical depression in psoriasis. A systematic literature search was conducted. Mean questionnaire values and proportions for depressive symptoms and clinical depression were pooled according to different assessment methods. In controlled studies, standardized mean differences (SMDs) and odds ratio (OR) compared depression in psoriasis patients with controls using the random-effect model. The majority of the 98 eligible studies were conducted in tertiary centers without a control group. The prevalence of depressive symptoms was 28% using questionnaires and the prevalence of clinical depression was 12% using International Classification of Diseases codes, 19% using Diagnostic and Statistical Manual of Mental Disorders IV, and 9% for antidepressant use. Psoriasis patients had significantly more depressive symptoms (SMD 1.16; 95% confidence interval (CI) 0.67-1.66), and population-based studies showed that they were at least one and a half times more likely to experience depression (OR 1.57; 95% CI 1.40-1.76) and used more antidepressants than did controls (OR 4.24, 95% CI 1.53-11.76). More than 10% of psoriasis patients suffer from clinical depression, and twice as many have depressive symptoms. The high prevalence of these symptoms is likely to be affected by the tertiary study populations and differential misclassification using questionnaires, where psoriasis-related symptoms may be detected as depressive symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.