Evidence map›Paper›PMID 24283882›Full record

ReviewEpigenomics2013

Epigenomics and allergic disease.

Gabrielle A Lockett, Veeresh K Patil, Nelís Soto-Ramírez, Ali H Ziyab, John W Holloway, Wilfried Karmaus

Open access · greenAbstract readReview
In one paragraph

Review in Epigenomics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Infant Feeding Practices During the First Postnatal Year and Risk of Asthma and Allergic Disease During the First 6 Years of Life.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2021
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. [Epigenetic effects of human breastfeeding].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2016
    Review
  14. Article
  15. Article
  16. Article
  17. Asthma genetics and personalised medicine.The Lancet. Respiratory medicine · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Gabrielle A LockettHuman Development & Health, Faculty of Medicine, University of Southampton, Southampton, UK.
Veeresh K Patil
Nelís Soto-Ramírez
Ali H Ziyab
John W Holloway
Wilfried Karmaus
University of Memphis · USUniversity of Southampton · GBKuwait University · KWSt Mary's Hospital · GB

Funding

Transgenerational epigenetic inheritance of allergy in a multigenerational cohortR01AI091905 · NIAID · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI KARMAUS, WILFRIED JJ · 2011 to 2015
$2.7M
Medical Research Council G0400473Medical Research Council G0800766Medical Research Council G0900453NIAID NIH HHS R01 AI091905NIAID NIH HHS R01 AI091905-01
6 · The paper itself

Abstract

Allergic disease development is affected by both genes and the environment, and epigenetic mechanisms are hypothesized to mediate these environmental effects. In this article, we discuss the link between the environment, DNA methylation and allergic disease, as well as questions of causality inherent to analyses of DNA methylation. From the practical side, we describe characteristics of allergic phenotypes and contrast different epidemiologic study designs used in epigenetic research. We examine methodological considerations, how best to conduct preprocessing and analysis of DNA methylation data sets, and the latest methods, technologies and discoveries in this rapidly advancing field. DNA methylation and other epigenetic marks are firmly entwined with allergic disease, a link that may hold the basis for future allergic disease diagnosis and treatment.

Indexed as

DNA MethylationEpigenesis, GeneticAge FactorsEpigenomicsFemaleHumansHypersensitivityMalePhenotype

Identifiers

PMID24283882
PMCPMC3951412
OpenAlexW2100856525

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.