ReviewInternational dental journal2013
Important considerations in the development of toothpaste formulations for children.
Review in International dental journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Comparative evaluation of the biocompatibility and antibacterial efficacy of various toothpaste formulations.Scientific reports · 2026Article
- Toothbrush and toothpaste preferences among Southern Saudi children: insights into oral hygiene awareness and practices.Frontiers in dental medicine · 2026Article
- Fluoride content in children's dentifrices marketed in Argentina.Acta odontologica latinoamericana : AOL · 2025Article
- Effect of a 1.1% NaF toothpaste containing Sr/F-doped bioactive glass on irradiated demineralized dentin: an in vitro study.BMC oral health · 2024Article
- A Qualitative Study of Preschool Children's Perspectives on an Oral Health Promotion Program in New South Wales, Australia.Children (Basel, Switzerland) · 2024Article
- A Study on the Biofilm Removal Efficacy of a Bioelectric Toothbrush.Bioengineering (Basel, Switzerland) · 2023Article
- Toothpaste Abrasion and Abrasive Particle Content: Correlating High-Resolution Profilometric Analysis with Relative Dentin Abrasivity (RDA).Dentistry journal · 2023Article
- Relationship between Toothpaste Dilution Ratio and Droplets Generated during Tooth-Brushing.International journal of environmental research and public health · 2022Article
- Evaluation of Abrasion and Whitening Effect of Toothpastes Containing Charcoal on Primary Teeth.Frontiers in dentistry · 2022Article
- Bioavailable fluoride in calcium-containing dentifrices.Scientific reports · 2021Article
- Dentifrices for children differentially affect cell viability in vitro.Clinical oral investigations · 2017Article
- In vitro assessment of a toothpaste range specifically designed for children.International dental journal · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A number of factors should be taken into account when designing toothpaste formulations for use by children at the different stages of their development. While adult toothpaste formulations may provide caries prevention benefits for children at risk of caries, these formulations may also contain higher levels of abrasive in order to address the staining needs of the adult population owing to smoking and the consumption of dietary chromogens such as coffee and tea, which are not normally found in the diet of children. While toothpastes formulated for adults are also likely to contain higher concentrations of surfactant and flavour, many children prefer toothpastes with mild flavours and modest foaming characteristics. An ideal children's toothpaste formulation should therefore aim to maximise fluoride availability, with appropriate abrasivity, while still delivering effective cleaning, as well as levels and types of flavour and surfactant to provide an acceptable brushing experience. Selection of toothpaste flavour types for children of different ages should ideally be based directly upon preference data from children. Flavours perceived as pleasant during brushing studies have been linked to increased brushing time, which, in turn, can increase the delivery and efficacy of fluoride from toothpastes. Therefore, manufacturers select tested, child-friendly flavours to maximise compliance, providing a more pleasurable brushing experience and oral health benefits.
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Registered trials
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