ArticleJournal of diabetes research2013
The impact of hyperglycemic emergencies on the kidney and liver.
Article in Journal of diabetes research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Effects ofJournal of microbiology and biotechnology · 2026Article
- Acid-base and electrolyte disorders in patients with hyperglycaemia: a monocentric, observational study.Clinical and experimental nephrology · 2025Observational
- Real-world insights from acute management of potassium disorders in diabetic ketoacidosis.Frontiers in endocrinology · 2025Article
- Association between blood urea nitrogen to serum albumin ratio and in-hospital mortality in critical patients with diabetic ketoacidosis: a retrospective analysis of the eICU database.Frontiers in endocrinology · 2024Article
- The impact of hyperglycaemic crisis episodes on long-term outcomes for inpatients presenting with acute organ injury: A prospective, multicentre follow-up study.Frontiers in endocrinology · 2022Article
- Semi-modified okara whey diet increased insulin secretion in diabetic rats fed a basal or high fat diet.Food science and biotechnology · 2021Article
- Hyperketonemia and ketosis increase the risk of complications in type 1 diabetes.Free radical biology & medicine · 2016Review
- Low Serum Levels of Prealbumin, Retinol Binding Protein, and Retinol Are Frequent in Adult Type 1 Diabetic Patients.Journal of diabetes research · 2016Article
- Surrogate markers of the kidney and liver in the assessment of gestational diabetes mellitus and fetal outcome.Journal of clinical and diagnostic research : JCDR · 2015Article
- Association between obesity and depression in patients with diabetes mellitus type 2; a study protocol.F1000Research · 2015Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies on the alterations of liver and kidney function parameters in patients with diabetic ketoacidosis (DKA) and diabetic ketosis (DK) were limited. Participants with DKA, DK, non-DK, and healthy controls were enrolled in the current study. Parameters of liver and kidney function were measured and evaluated. The patients with DKA had higher levels of plasma glucose, hemoglobin A1c (HbA1c), uric acid, and creatinine but lower levels of transferases and protein compared with the other three groups (P < 0.05 for all). The patients with DK had higher levels of plasma glucose and HbA1c but lower levels of glutamyl transpeptidase and protein compared with the non-DK and control groups (P < 0.05). Prealbumin levels were significantly reduced in the severe DKA patients compared with the mild/moderate DKA patients. Serum prealbumin levels were correlated with albumin levels (r = 0.401, P = 0.010), HCO3 (r = 0.350, P = 0.027), and arterial pH (r = 0.597, P < 0.001) in the DKA patients. A diagnostic analysis showed that lower prealbumin levels significantly reflected the presence of hyperglycemic emergencies (P < 0.001). Liver and kidney function parameters deteriorated, especially in DKA. Prealbumin levels can be of value in detecting the presence of hyperglycemic crisis. This clinical trial is registered with ChiCTR-OCH-12003077.
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