Evidence map›Paper›PMID 24282511›Full record

Trial reportPloS one2013

Cost-effectiveness of one year dementia follow-up care by memory clinics or general practitioners: economic evaluation of a randomised controlled trial.

Els Meeuwsen, René Melis, Geert van der Aa, Gertie Golüke-Willemse, Benoit de Leest, Frank van Raak, Carla Schölzel-Dorenbos, Desiree Verheijen, Frans Verhey, Marieke Visser and 3 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00554047 (Effectiveness and Costs of Post-diagnosis Treatment in Dementia Coordinated by Multidisciplinary Memory Clinics in Comparison to Treatment Coordinated by General Practitioners), which is not on this map. Cited by 19 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 8 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00554047 nacompletednot on this map

Effectiveness and Costs of Post-diagnosis Treatment in Dementia Coordinated by Multidisciplinary Memory Clinics in Comparison to Treatment Coordinated by General Practitioners

TypeinterventionalSponsorRadboud University Medical CenterRan2007 to 2010Enrolled220ConditionsDementiaArmsMultidisciplinary Memory Clinic, General Practitioners
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 8 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  4. Effectiveness of different post-diagnostic dementia care models delivered by primary care: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020
    Pooled it
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  7. Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Article
  12. On spillovers in economic evaluations: definition, mapping review and research agenda.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
    Review
  13. Review
  14. Article
  15. Article
  16. Article
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  19. Care of community-dwelling older adults with dementia and their caregivers.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Els MeeuwsenDepartment of Geriatrics/Radboud Alzheimer Centre, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands.
René Melis
Geert van der Aa
Gertie Golüke-Willemse
Benoit de Leest
Frank van Raak
Carla Schölzel-Dorenbos
Desiree Verheijen
Frans Verhey
Marieke Visser
Claire Wolfs
Eddy Adang
Marcel Olde Rikkert
Radboud University Medical Center · NLMaastricht University Medical Centre · NLAmsterdam Neuroscience · NLCatharina Ziekenhuis · NLElkerliek Ziekenhuis · NLGGZ Oost Brabant · NLRadboud University Nijmegen · NLRijnstate Hospital · NLSlingeland Ziekenhuis · NLZiekenhuis Gelderse Vallei · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the cost-effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared to general practitioners' care.

methodsA multicentre randomised trial with 175 community dwelling patients newly diagnosed with mild to moderate dementia, and their informal caregivers, with twelve months' follow-up. Cost-effectiveness was evaluated from a societal point of view and presented as incremental cost per quality adjusted life year. To establish cost-effectiveness, a cost-utility analysis was conducted using utilities based on the EQ-5D. Uncertainty surrounding the incremental cost-effectiveness ratio (difference in costs divided by difference in effects) was calculated by bootstrapping from the original data.

resultsCompared to general practitioners' care, treatment by the memory clinics was on average €1024 (95% CI: -€7723 to €5674) cheaper, and showed a non-significant decrease of 0.025 (95% CI: -0.114 to 0.064) quality adjusted life years. The incremental cost-effectiveness point estimate from the bootstrap simulation was € 41 442 per QALY lost if one would use memory clinic care instead of general practitioner care.

conclusionNo evidence was found that memory clinics were more cost-effective compared to general practitioners with regard to post-diagnosis treatment and coordination of care of patients with dementia in the first year after diagnosis.

trial registrationClinicalTrials.gov NCT00554047.

Indexed as

Cost-Benefit AnalysisQuality-Adjusted Life YearsAgedAged, 80 and overAmbulatory Care FacilitiesCaregiversDementiaFemaleFollow-Up StudiesGeneral PractitionersHumansMaleMemoryQuality of Life

Identifiers

PMID24282511
PMCPMC3839971
OpenAlexW2049984431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.