Evidence map›Paper›PMID 24282395›Full record

ReviewFrontiers in cellular neuroscience2013

Emerging neurotrophic role of GABAB receptors in neuronal circuit development.

Jean-Luc Gaiarsa, Christophe Porcher

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Review
  3. Evidence for Two Subpopulations of Cerebrospinal Fluid-Contacting Neurons with Opposite GABAergic Signaling in Adult Mouse Spinal Cord.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Keeping the Balance: GABABrain sciences · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. GABAFrontiers in cellular neuroscience · 2021
    Article
  13. Review
  14. Neonatal Clonazepam Administration Induced Long-Lasting Changes in GABAInternational journal of molecular sciences · 2020
    Article
  15. Preserving Inhibition during Developmental Hearing Loss Rescues Auditory Learning and Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  16. Article
  17. CaMolecular neurobiology · 2019
    Article
  18. Article
  19. GABAThe Journal of physiology · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jean-Luc GaiarsaInstitut National de la Santé et de la Recherche Médicale U-901 Marseille, France ; Aix-Marseille Université, UMR S901 Marseille, France ; Institut de Neurobiologie de la Méditerranée Marseille, France.
Christophe Porcher
Inserm · FRInstitut de Neurobiologie de la Méditerranée · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The proper development of highly organized structures in the central nervous system is a complex process during which key events - neurogenesis, migration, growth, differentiation, and synaptogenesis - have to take place in an appropriate manner to create functional neuronal networks. It is now well established that GABA, the main inhibitory neurotransmitter in the adult mammalian brain, plays more than a classical inhibitory role and can function as an important developmental signal early in life. GABA binds to chloride-permeable ionotropic GABAA receptors and to G-protein-coupled GABAB receptors (GABAB-Rs). Although most of the trophic actions of GABA have been attributed to the activation of GABAA receptors, recent advances show that GABAB-Rs also regulate fundamental steps of network development. This review summarizes some of the recent progress about the neurotrophic role of GABAB-Rs to neuronal development.

Indexed as

cortical developmentGABAGABAB receptorsmigrationsynaptogenesis

Identifiers

PMID24282395
PMCPMC3824957
OpenAlexW2114954808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.