ArticleEuropean journal of clinical nutrition2014
An approach to quantifying abnormalities in energy expenditure and lean mass in metabolic disease.
Article in European journal of clinical nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- TRIAC Therapy Relieves Hyperthyroid Symptoms, Lowering T4, T3, and Metabolic Rate in Resistance to Thyroid Hormone β.The Journal of clinical endocrinology and metabolism · 2026Article
- SMIM1 absence is associated with reduced energy expenditure and excess weight.Med (New York, N.Y.) · 2024Article
- Centile reference chart for resting metabolic rate through the life course.Archives of disease in childhood · 2023Article
- Resistance to thyroid hormone induced tachycardia in RTHα syndrome.Nature communications · 2023Article
- Room Indirect Calorimetry Operating and Reporting Standards (RICORS 1.0): A Guide to Conducting and Reporting Human Whole-Room Calorimeter Studies.Obesity (Silver Spring, Md.) · 2020Review
- Descriptive epidemiology of energy expenditure in the UK: findings from the National Diet and Nutrition Survey 2008-15.International journal of epidemiology · 2020Article
- Estimating physical activity from self-reported behaviours in large-scale population studies using network harmonisation: findings from UK Biobank and associations with disease outcomes.The international journal of behavioral nutrition and physical activity · 2020Article
- Short-term Change in Resting Energy Expenditure and Body Compositions in Therapeutic Process for Graves' Disease.Internal medicine (Tokyo, Japan) · 2020Article
- Estimating energy expenditure from wrist and thigh accelerometry in free-living adults: a doubly labelled water study.International journal of obesity (2005) · 2019Article
- Quantifying energy expenditure in childhood: utility in managing pediatric metabolic disorders.The American journal of clinical nutrition · 2019Article
- Normalizing resting energy expenditure across the life course in humans: challenges and hopes.European journal of clinical nutrition · 2018Review
- Article
- The Importance of Hydration in Body Composition Assessment in Children Aged 6-16 Years.Journal of clinical densitometry : the official journal of the International Society for Clinical DensitometryArticle
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Authors and funding
9 authors.
Funding
Abstract
BACKGROUND/
objectivesThe objective of this study was to develop approaches to expressing resting energy expenditure (REE) and lean body mass (LM) phenotypes of metabolic disorders in terms of Z-scores relative to their predicted healthy values. SUBJECTS/
methodsBody composition and REE were measured in 135 healthy participants. Prediction equations for LM and REE were obtained from linear regression and the range of normality by the standard deviation of residuals. Application is demonstrated in patients from three metabolic disorder groups (lipodystrophy, n=7; thyrotoxicosis, n=16; and resistance to thyroid hormone (RTH), n=46) in which altered REE and/or LM were characterised by departure from the predicted healthy values, expressed as a Z-score.
resultsREE (kJ/min) = -0.010 × age (years)+0.016 × FM (kg)+0.054 × fat-free mass (kg)+1.736 (R2 = 0.732, RSD = 0.36 kJ/min). LM (kg)=5.30 × bone mineral content (kg)+10.66 × height2 (m)+6.40 (male). LM (kg)=0.20 × fat (kg)+14.08 × height2 (m)-2.93 (female).(male R2=0.55, RSD = 3.90 kg; female R2 = 0.59, RSD=3.85 kg).We found average Z-scores for REE and LM of 1.77 kJ/min and -0.17 kg in the RTH group, 5.82 kJ/min and -1.23 kg in the thyrotoxic group and 2.97 kJ/min and 4.20 kg in the LD group.
conclusionThis approach enables comparison of data from individuals with metabolic disorders with those of healthy individuals, describing their departure from the healthy mean by a Z-score.
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