Evidence map›Paper›PMID 24281271›Full record

Trial reportThe Clinical journal of pain2014

Caregiver's perceptions of the relationship of pain to behavioral and psychiatric symptoms in older community-residing adults with dementia.

Nancy Hodgson, Laura N Gitlin, Laraine Winter, Walter W Hauck

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Clinical journal of pain, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06264362 (Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06264362 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia

TypeinterventionalSponsorDrexel UniversityRan2025 to 2027Enrolled40ConditionsPain, Chronic, Dementia, Mild, Mobility Limitation, Physical DisabilityArmsTailored Physical Activity Program
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Problem Adaptation Therapy for Older Adults with Chronic Pain and Negative Emotions in Primary Care (PATH-Pain): A Randomized Clinical Trial.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025
    Trial
  3. Trial
  4. Article
  5. Article
  6. Health Information-Seeking Behavior of Latino Caregivers of People Living with Dementia: A Mixed-Methods Study.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nancy Hodgson*School of Nursing, Johns Hopkins University, Baltimore, MD †Philadelphia VA Medical Center, Philadelphia, PA ‡Sycamore Consulting LLC, Woodstock, GA.
Laura N Gitlin
Laraine Winter
Walter W Hauck
Johns Hopkins University · USPhiladelphia VA Medical Center · US

Funding

Reducing Family Caregiver Upset with Disruptive BehaviorR01AG022254 · NIA · THOMAS JEFFERSON UNIVERSITY · PI GITLIN, LAURA N. · 2002 to 2006
$2.7M
Physiologic Distress and Neuropsychiatric Behaviors in Alzheimer's DiseaseK23NR012017 · NINR · JOHNS HOPKINS UNIVERSITY · PI HODGSON, NANCY A · 2010 to 2012
$368k
NIA NIH HHS R01 AG022254NIA NIH HHS R01 AG22254NINR NIH HHS K23 NR012017
6 · The paper itself

Abstract

objectivesPain is underrecognized and undermanaged in older adults with dementia. Because dementia patients have a diminished capacity to communicate discomfort, untreated pain may be expressed in the form of behavioral and psychiatric symptoms. The goal of the present study was to examine the relationship between pain and behavioral and psychiatric symptoms of dementia in community-residing older adults from the perspective of the family caregiver. MATERIALS AND

methodsDyads composed of 272 dementia patients, and their family caregivers were assessed to determine dementia patient's mental status; family caregiver's assessment of care recipient's pain, functional dependence, and number of behavioral symptoms; analgesic use; and demographic information.

resultsHierarchical multiple regression analysis controlling for age, marital status, race, functional disability, and analgesic use showed that pain explained a small but significant percent of variance in the number of behavioral symptoms (3%, P<0.001). Pain had a stronger influence on the number of behavioral and psychiatric symptoms of dementia among those with severe cognitive impairment (F1,69=11.75, P<0.001) compared with those with low to moderate cognitive impairment (F1,199=4.543, P=0.034.). DISCUSSION: The findings indicate that pain is a risk factor for behavioral symptoms in individuals with dementia and suggest that pain is a more significant predictor of behavior for individuals with severe dementia, compared with those with mild/moderate stage dementia. These results reinforce the importance of proper pain assessment and its management as part of dementia care planning.

Indexed as

AgedAgingBehavioral SymptomsCaregiversCognition DisordersDementiaFemaleHumansMaleMental Status ScheduleMiddle AgedPainPain PerceptionRegression AnalysisResidence CharacteristicsRetrospective Studies

Identifiers

PMID24281271
PMCPMC3995132
OpenAlexW1979031746

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.