ArticleJournal of oncology practice2014
Screening for depressed mood in patients with cancer using the MD Anderson Symptom Inventory: investigation of a practical approach for the oncologist.
Article in Journal of oncology practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Perioperative trajectory of patient reported symptoms: a pilot study in gynecologic oncology patients.Gynecologic oncology · 2015Trial
- The association between loneliness and quality of life in cancer survivors: All of Us research program.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Predictors of Psychiatric Complications in Patients with Pancreatic Cancer: A Retrospective Cohort Study.Actas espanolas de psiquiatria · 2024Article
- Development and validation of clinical implementation methods for patient-reported outcomes in Japanese multi-center palliative care units.Journal of patient-reported outcomes · 2024Article
- Screening for Distress and Health Outcomes in Head and Neck Cancer.Current oncology (Toronto, Ont.) · 2022Observational
- Patient-reported outcomes in light of supportive medications in treatment-naïve lung cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Lack of Patient-Clinician Concordance in Cancer Patients: Its Relation With Patient Variables.Journal of pain and symptom management · 2017Article
- A Prospective Evaluation of the Effects of Prevalent Depressive Symptoms on Disease Activity in Rheumatoid Arthritis Patients Treated With Biologic Response Modifiers.Clinical therapeutics · 2016Article
- Posttraumatic stress and depressive symptoms in renal cell carcinoma: association with quality of life and utility of single-item distress screening.Psycho-oncology · 2015Article
- Patterns and predictors of antidepressant use in ambulatory cancer patients with common solid tumors.Psycho-oncology · 2015Observational
- Temporal effect of depressive symptoms on the longitudinal evolution of rheumatoid arthritis disease activity.Arthritis care & research · 2015Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
purposeDepression is a significant concern in outpatient oncology care, yet clinicians face practical challenges in accurately and efficiently screening patients for it. This study investigated whether a single item or multiple items from an existing multisymptom scale, the MD Anderson Symptom Inventory (MDASI), might serve as effective initial screens for depressed mood.
methodsData were collected from two cohorts of patients. Cohort 1 comprised 187 patients with non-small-cell lung cancer who completed the Beck Depression Inventory II; cohort 2 comprised 281 patients with renal cell carcinoma who completed the Center for Epidemiologic Studies Depression Scale. All patients completed the MDASI. Single-item and multiple-item MDASI solutions were identified using cohort 1 and validated in cohort 2. Sensitivity and specificity of the solutions were assessed through binary linear regression; cut points were identified using receiver operating characteristic analysis.
resultsThe MDASI single item "sadness" was the best solution identified in cohort 1 for screening for depressed mood relative to other affective items (distress, enjoyment of life, mood). At a cut point ≥ 4 (0 to 10 scale), the "sadness" item exhibited a clinically acceptable specificity of 81.5%, sensitivity of 72.0%, a negative predictive value of 95.0%, and a positive predictive value of 37.5%. This solution was successfully validated in cohort 2.
conclusionThe MDASI "sadness" item has modest sensitivity and high negative predictive value and can serve as a useful initial screen for depressed mood. This approach may improve the efficiency and acceptability of depression screening for both clinicians and patients.
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