Evidence map›Paper›PMID 24281053›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2014

Too Fit To Fracture: exercise recommendations for individuals with osteoporosis or osteoporotic vertebral fracture.

L M Giangregorio, A Papaioannou, N J Macintyre, M C Ashe, A Heinonen, K Shipp, J Wark, S McGill, H Keller, R Jain and 2 more

3 registry-linked trialsAbstract readConsensus Statement
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 117 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 12 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04037436 nacompletednot on this mapstarted 2019, after this paper: background citation

A Model for Delivering Strength Training and Nutrition Education for Older Adults (MoveStrong): A Pilot Randomized Controlled Trial

TypeinterventionalSponsorUniversity of WaterlooRan2019 to 2020Enrolled44ConditionsChronic Disease, Frail, Diabetes Mellitus, CancerArmsStrength and Balance Training & Nutrition Education, Usual Care
NCT05521724 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect of Exercise Training on Individuals With Osteoporotic Vertebral Fractures

TypeinterventionalSponsorHasan Kalyoncu UniversityRan2022 to 2022Enrolled40ConditionsExercise Addiction, Vertebral FractureArmsexercise
NCT07685392 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of a Progressive Strength and Balance Exercise Program on Falls in Postmenopausal Women With Osteoporosis: A Randomized Controlled Pilot Trial

TypeinterventionalSponsorInstituto Nacional de RehabilitacionRan2023 to 2025Enrolled46ConditionsPostmenopausal Osteoporosis, Accidental Falls, Aged, Exercise Movement Techniques, Fragility FracturesArmsSupervised Progressive Strength and Balance Exercise Program, Home-Based Conventional Exercise Program
3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 12 syntheses or guidelines pooled it, 239 citations in OpenAlex.

  1. High-intensity resistance and impact exercise in menopausal women: a systematic review of intervention reporting quality and training content.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Effects of non-supervised exercise interventions on bone mineral density in adult women: a systematic review and meta‑analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Exercise for improving outcomes after osteoporotic vertebral fracture.The Cochrane database of systematic reviews · 2019
    Pooled it
  11. Exercise to improve functional outcomes in persons with osteoporosis: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Pooled it
  12. The effects of person-centered or other supportive interventions in older women with osteoporotic vertebral compression fractures-a systematic review of the literature.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Pooled it
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Encouraging older adults with pre-frailty and frailty to "MoveStrong": an analysis of secondary outcomes for a pilot randomized controlled trial.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2022
    Trial
  18. Trial
  19. Trial
  20. Effects of a resistance and balance exercise programme on physical fitness, health-related quality of life and fear of falling in older women with osteoporosis and vertebral fracture: a randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Trial

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 4 countries.

L M GiangregorioDepartment of Kinesiology, University of Waterloo, 200 University Ave, Waterloo, ON, N2L 3G1, Canada, lora.giangregorio@uwaterloo.ca.
A Papaioannou
N J Macintyre
M C Ashe
A Heinonen
K Shipp
J Wark
S McGill
H Keller
R Jain
J Laprade
A M Cheung
University of Waterloo · CAMcMaster University · CAUniversity of Toronto · CADuke University · USOsteoporosis Canada · CAThe Royal Melbourne Hospital · AUUniversity of British Columbia · CAUniversity of Jyväskylä · FI

Funding

CIHR 88225-1
6 · The paper itself

Abstract

summaryA consensus process was conducted to develop exercise recommendations for individuals with osteoporosis or vertebral fractures. A multicomponent exercise program that includes balance and resistance training is recommended.

introductionThe aim was to develop consensus on exercise recommendations for older adults: (1) with osteoporosis and (2) with osteoporotic vertebral fracture(s).

methodsThe Grading of Recommendations Assessment, Development, and Evaluation method was used to evaluate the quality of evidence and develop recommendations. Outcomes important for decision making were nominated by an expert panel and patient advocates. They included falls, fractures, bone mineral density (BMD), and adverse events for individuals with osteoporosis/vertebral fractures, and pain, quality of life, and function for those with vertebral fracture. Meta-analyses evaluating the effects of exercise on the outcomes were reviewed. Observational studies or clinical trials were reviewed when meta-analyses were not available. Quality ratings were generated, and informed the recommendations.

resultsThe outcome for which evidence is strongest is falls. Point estimates of the effects of exercise on falls, fractures, and BMD vary according to exercise type. There is not enough evidence to quantify the risks of exercise in those with osteoporosis or vertebral fracture. Few trials of exercise exist in those with vertebral fracture. The exercise recommendations for exercise in individuals with osteoporosis or osteoporotic vertebral fracture are conditional. The panel strongly recommends a multicomponent exercise program including resistance and balance training for individuals with osteoporosis or osteoporotic vertebral fracture. The panel recommends that older adults with osteoporosis or vertebral fracture do not engage in aerobic training to the exclusion of resistance or balance training.

conclusionsThe consensus of our international panel is that exercise is recommended for older adults with osteoporosis or vertebral fracture, but our recommendations are conditional.

Indexed as

Accidental FallsActivities of Daily LivingAdultAgedBone DensityEvidence-Based MedicineExercise TherapyHumansMiddle AgedOsteoporosisOsteoporotic FracturesPostural BalanceQuality of LifeResistance Training

Identifiers

PMID24281053
PMCPMC5112023
OpenAlexW2016083467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.