ReviewJournal of psychiatry & neuroscience : JPN2014
Possible role of more positive social behaviour in the clinical effect of antidepressant drugs.
Review in Journal of psychiatry & neuroscience : JPN, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Exercise and yoga during pregnancy and their impact on depression: a systematic literature review.Archives of women's mental health · 2022Pooled it
- Affect, interpersonal behaviour and interpersonal perception during open-label, uncontrolled paroxetine treatment of people with social anxiety disorder: a pilot studyJournal of psychiatry & neuroscience : JPN · 2018Trial
- Preclinical Models of Chronic Stress: Adaptation or Pathology?Biological psychiatry · 2023Review
- Relationship between change in social evaluation learning and mood in early antidepressant treatment: A prospective cohort study in primary care.Journal of psychopharmacology (Oxford, England) · 2023Article
- Article
- Symptom Cluster-Matching Antidepressant Treatment: A Case Series Pilot Study.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Emotional and interpersonal mechanisms in community SSRI treatment of social anxiety disorder.Journal of psychiatry & neuroscience : JPN · 2021Article
- Autism biomarkers: challenges, pitfalls and possibilities.Journal of autism and developmental disorders · 2015Review
- The Effects of Tryptophan on Everyday Interpersonal Encounters and Social Cognitions in Individuals with a Family History of Depression.The international journal of neuropsychopharmacology · 2015Article
- The ability of early changes in motivation to predict later antidepressant treatment response.Neuropsychiatric disease and treatment · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing serotonin decreases quarrelsome behaviours and enhances agreeable behaviours in humans. Antidepressants, even those whose primary action is not on serotonin, seem to increase serotonin function. We suggest that antidepressants act in part by effects on social behaviour, which leads to a gradual improvement in mood. We review the evidence supporting the idea that antidepressants may be moving behaviour from quarrelsome to agreeable. The more positive social responses of interaction partners would initiate a cycle of more positive social behaviour, and this iterative process would result in a clinically significant improvement in mood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.