ArticleFrontiers in zoology2013
More than royal food - Major royal jelly protein genes in sexuals and workers of the honeybee Apis mellifera.
Article in Frontiers in zoology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 95 citations in OpenAlex.
- Exploratory Characterization of Artisanal Royal Jelly Produced byFoods (Basel, Switzerland) · 2026Article
- Ectopic expression of structurally similar major royal jelly proteins reveals their distinct functions inJournal of Zhejiang University. Science. B · 2026Article
- Molecular Adjustment to a Social Niche: Brain Transcriptomes Reveal Divergent Influence of Social Environment on the Two Queen Morphs of the Ant Temnothorax rugatulus.Molecular ecology · 2025Article
- Differences in the suitability of published honey bee (Apis mellifera) reference genes between the African subspecies Apis mellifera scutellata and European derived Apis mellifera.Molecular ecology · 2025Article
- Royal Jelly Enhances the Social Status of Submissive Rats by Restoring Balance to the Disturbed Gut-Brain Communication.Foods (Basel, Switzerland) · 2025Article
- Molecular Basis of Eusocial Complexity: The Case of Worker Reproductivity in Bees.Genome biology and evolution · 2024Article
- Bee products: An overview of sources, biological activities and advanced approaches used in apitherapy application.Biotechnology reports (Amsterdam, Netherlands) · 2024Review
- Urbanization Shifts Immunometabolism in a Common Bumblebee.Ecology and evolution · 2024Article
- Chemical Composition and Nutritional Value of Royal Jelly Samples Obtained from Honey Bee (Insects · 2024Article
- Behavioral and genetic correlates of heterogeneity in learning performance in individual honeybees, Apis mellifera.PloS one · 2024Article
- Mediating a host cell signaling pathway linked to overwinter mortality offers a promising therapeutic approach for improving bee health.Journal of advanced research · 2023Article
- Ferroptosis precedes apoptosis to facilitate specific death signalling by fatty acids.Proceedings. Biological sciences · 2023Article
- Revolutionizing the Use of Honeybee Products in Healthcare: A Focused Review on Using Bee Pollen as a Potential Adjunct Material for Biomaterial Functionalization.Journal of functional biomaterials · 2023Review
- Identification of royal jelly as a potential new drug to protect the ovarian reserve and uterus against cyclophosphamide in rats.Clinical and experimental reproductive medicine · 2023Article
- Current Status of the Bioactive Properties of Royal Jelly: A Comprehensive Review with a Focus on Its Anticancer, Anti-Inflammatory, and Antioxidant Effects.Molecules (Basel, Switzerland) · 2023Review
- Article
- Royal Jelly Components Encapsulation in a Controlled Release System-Skin Functionality, and Biochemical Activity for Skin Applications.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Expression of MRJP3 and HSP70 mRNA Levels inInsects · 2022Article
- Extent and complexity of RNA processing in honey bee queen and worker caste development.iScience · 2022Article
- Ameliorative effect of bee products onVeterinarni medicina · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the honeybee Apis mellifera, female larvae destined to become a queen are fed with royal jelly, a secretion of the hypopharyngeal glands of young nurse bees that rear the brood. The protein moiety of royal jelly comprises mostly major royal jelly proteins (MRJPs) of which the coding genes (mrjp1-9) have been identified on chromosome 11 in the honeybee's genome.
resultsWe determined the expression of mrjp1-9 among the honeybee worker caste (nurses, foragers) and the sexuals (queens (unmated, mated) and drones) in various body parts (head, thorax, abdomen). Specific mrjp expression was not only found in brood rearing nurse bees, but also in foragers and the sexuals.
conclusionsThe expression of mrjp1 to 7 is characteristic for the heads of worker bees, with an elevated expression of mrjp1-4 and 7 in nurse bees compared to foragers. Mrjp5 and 6 were higher in foragers compared to nurses suggesting functions in addition to those of brood food proteins. Furthermore, the expression of mrjp9 was high in the heads, thoraces and abdomen of almost all female bees, suggesting a function irrespective of body section. This completely different expression profile suggests mrjp9 to code for the most ancestral major royal jelly protein of the honeybee.
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