ArticleBMC public health2013
Predictors of antibiotics co-prescription with antimalarials for patients presenting with fever in rural Tanzania.
Article in BMC public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Prevalence of fever of unidentified aetiology in East African adolescents and adults: a systematic review and meta-analysis.Infectious diseases of poverty · 2023Pooled it
- Antimicrobial prescription patterns in East Africa: a systematic review.Systematic reviews · 2023Pooled it
- Diagnosing acute and prevalent HIV-1 infection in young African adults seeking care for fever: a systematic review and audit of current practice.International health · 2014Pooled it
- Community-Based Malaria Testing Reduces Polypharmacy in a Population-Based Survey of Febrile Illness in Western Kenya.International journal of public health · 2022Trial
- Patterns of antibiotic use for acute febrile illness in resource-limited settings: a multicenter study in DR Congo, Kenya and Uganda.Frontiers in public health · 2026Article
- Antimicrobial Stewardship in Tropical Infectious Diseases: Focusing on Dengue and Malaria.Tropical medicine and infectious disease · 2022Review
- Adherence to standard treatment guidelines among prescribers in primary healthcare facilities in the Dodoma region of Tanzania.BMC health services research · 2021Article
- Infection Manager System (IMS) as a new hemocytometry-based bacteremia detection tool: A diagnostic accuracy study in a malaria-endemic area of Burkina Faso.PLoS neglected tropical diseases · 2021Article
- The prevalence and pattern of antibiotic prescription among insured patients in Dar es Salaam Tanzania.The Pan African medical journal · 2021Article
- Management of uncomplicated malaria among children under five years at public and private sector facilities in Mali.BMC public health · 2020Article
- Drug use in the management of uncomplicated malaria in public health facilities in the Democratic Republic of the Congo.Malaria journal · 2018Article
- Predictors of residual antimalarial drugs in the blood in community surveys in Tanzania.PloS one · 2018Article
- Profile of C-reactive protein, white cells and neutrophil populations in febrile children from rural north-eastern Tanzania.The Pan African medical journal · 2017Article
- Bloodstream bacterial infection among outpatient children with acute febrile illness in north-eastern Tanzania.BMC research notes · 2015Article
- Poor adherence to the malaria management protocol among health workers attending under-five year old febrile children at Omdurman Hospital, Sudan.Malaria journal · 2015Article
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSuccessful implementation of malaria treatment policy depends on the prescription practices for patients with malaria. This paper describes prescription patterns and assesses factors associated with co-prescription of antibiotics and artemether-lumefantrine (AL) for patients presenting with fever in rural Tanzania.
methodFrom June 2009 to September 2011, a cohort event monitoring program was conducted among all patients treated at 8 selected health facilities in Ifakara and Rufiji Health and Demographic Surveillance System (HDSS). It included all patients presenting with fever and prescribed with AL. Logistic regression was used to model the predictors on the outcome variable which is co-prescription of AL and antibiotics on a single clinical visit.
resultsA cohort of 11,648 was recruited and followed up with 92% presenting with fever. Presumptive treatment was used in 56% of patients treated with AL. On average 2.4 (1 - 7) drugs was prescribed per encounter, indicating co-prescription of AL with other drugs. Children under five had higher odds of AL and antibiotics co-prescription (OR = 0.63, 95% CI: 0.46 - 0.85) than those aged more than five years. Patients testing negative had higher odds (OR = 2.22, 95% CI: 1.65 - 2.97) of AL and antibiotics co-prescription. Patients receiving treatment from dispensaries had higher odds (OR = 1.45, 95% CI: 0.84 - 2.30) of AL and antibiotics co-prescription than those served in health centres even though the deference was not statistically significant.
conclusionRegardless the fact that Malaria is declining but due to lack of laboratories and mRDT in most health facilities in the rural areas, clinicians are still treating malaria presumptively. This leads them to prescribe more drugs to treat all possibilities.
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