ReviewScientifica2012
Clinical pharmacology in old persons.
Review in Scientifica, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05902676 (The Effects Of Anticholinergic Burden On Daily Living Activities In Elderly Patients), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects Of Anticholinergic Burden On Daily Living Activities In Elderly Patients
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Use of geriatric assessment in cancer clinical trials: A systematic review.Journal of geriatric oncology · 2022Pooled it
- Comparison of Remimazolam versus Dexmedetomidine on Hemodynamics in Older Patients Under Lower Extremity Orthopedic Surgery with Spinal Anesthesia: A Randomized Controlled Trial.Drug design, development and therapy · 2025Trial
- Opti-Med: the effectiveness of optimised clinical medication reviews in older people with 'geriatric giants' in general practice; study protocol of a cluster randomised controlled trial.BMC geriatrics · 2014Trial
- The impact of age on the survival outcomes of hepatocellular carcinoma patients after transarterial chemoembolization: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2025Review
- Article
- Innovative Approaches to Enhance and Measure Medication Adherence in Chronic Disease Management: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- Effectiveness and drug retention of biologic disease modifying antirheumatic drugs in Korean patients with late onset ankylosing spondylitis.Scientific reports · 2021Article
- Medication Review in Preventing Older Adults' Fall-Related Injury: a Systematic Review & Meta-Analysis.Canadian geriatrics journal : CGJ · 2021Article
- Determinants of community pharmacy utilisation among the adult population in Malaysia: findings from the National Health and Morbidity Survey 2019.BMC health services research · 2021Article
- Healthy aging and the blood-brain barrier.Nature aging · 2021Review
- Prescribing medicines to older people-How to consider the impact of ageing on human organ and body functions.British journal of clinical pharmacology · 2020Review
- Anticholinergic Drug Induced Cognitive and Physical Impairment: Results from the InCHIANTI Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Real-World Safety and Effectiveness of Tadalafil in Patients with Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia: A Japanese Post-Marketing Surveillance Study.Pragmatic and observational research · 2020Article
- Clinical Results of Comprehensive Medication Management Services in Primary Care in Belo Horizonte.Pharmacy (Basel, Switzerland) · 2019Article
- A Comprehensive Overview of Polypharmacy in Elderly Patients in Saudi Arabia.Geriatrics (Basel, Switzerland) · 2019Article
- Factors associated with the use of potentially inappropriate medication by elderly patients prescribed at hospital discharge.Einstein (Sao Paulo, Brazil) · 2019Article
- Prescribing issues in older adults living with HIV: thinking beyond drug-drug interactions with antiretroviral drugs.Therapeutic advances in drug safety · 2019Article
- Tyrosine Kinase Inhibitors and Proton Pump Inhibitors: An Evaluation of Treatment Options.Clinical pharmacokinetics · 2017Article
- Are We Using Slow-Acting Symptomatic Chondroprotective Drugs Conscious Enough?The open orthopaedics journal · 2017Article
- Information on actual medication use and drug-related problems in older patients: questionnaire or interview?International journal of clinical pharmacy · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The epidemiological transition, with a rapid increase in the proportion in the global population aged over 65 years from 11% in 2010 to 22% in 2050 and 32% in 2100, represents a challenge for public health. More and more old persons have multimorbidities and are treated with a large number of medicines. In advanced age, the pharmacokinetics and pharmacodynamics of many drugs are altered. In addition, pharmacotherapy may be complicated by difficulties with obtaining drugs or adherence and persistence with drug regimens. Safe and effective pharmacotherapy remains one of the greatest challenges in geriatric medicine. In this paper, the main principles of geriatric pharmacology are presented.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.