ArticlePostepy dermatologii i alergologii2013
The role of focal infections in the pathogenesis of psoriasis and chronic urticaria.
Article in Postepy dermatologii i alergologii, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Infections and the risk of psoriatic arthritis among psoriasis patients: a systematic review.Rheumatology international · 2018Pooled it
- Case Report: Resolution of chronic urticaria following treatment of odontogenic infection.F1000Research · 2018Article
- MicroRNA-181b negatively regulates the proliferation of human epidermal keratinocytes in psoriasis through targeting TLR4.Journal of cellular and molecular medicine · 2017Article
- Refractory chronic spontaneous urticaria and permanent atrial fibrillation associated with dental infection: Mere coincidence or something more to it?International journal of immunopathology and pharmacology · 2016Article
- Temperament and character profiles of patients with chronic idiopathic urticaria.Postepy dermatologii i alergologii · 2015Article
- Effectiveness of omalizumab in a patient with a life-threatening episode of bronchospasm and larynx angioedema after exposure to house dust.Postepy dermatologii i alergologii · 2014Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe Focal Infection Theory, originally presented at the beginning of the 20(th) century, postulates that systemic diseases can be caused by microorganisms that arise from the focus of infection. Foci of infections have been described as sinuses, adenoids, tonsils, teeth, genitourinary tract, gall bladder and kidneys. A focus of infection is defined as the area that can occur in any part of the body, contains a pathogen (microorganism) and is usually asymptomatic. There are discordant opinions about the role of focal infections in the pathogenesis of psoriasis and urticaria.
aimTo establish whether there is a higher incidence of focal infections in patients with chronic urticaria and psoriasis. MATERIAL AND
methodsWe retrospectively reviewed 129 patients with a history of psoriasis and chronic urticaria: 58 women and 71 men treated in the Department of Dermatology of the Jagiellonian University Medical College in Krakow.
resultsIn the analyzed group, 11 patients had a dental consultation, 58 - laryngological consultation and 29 women had a gynecological consultation. The most common examples of focal infection were tonsillitis, upper respiratory tract infections, sinusitis, dental caries and genitourinary tract infections. Aggravating factors were similar to previously described.
conclusionsA high incidence of focal infections in patients with psoriasis and urticaria suggests that infections may play a significant role in the pathogenesis of these skin disorders. Treatment of infection foci may play the key role in the remission of skin changes.
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