ArticleMolecular and cellular biochemistry2014
miR-141 suppresses proliferation and motility of gastric cancer cells by targeting HDGF.
Article in Molecular and cellular biochemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Screening and validation of novel serum panel of microRNA in stratification of prostate cancer.Prostate international · 2023Article
- Cancer and Alzheimer's Inverse Correlation: an Immunogenetic Analysis.Molecular neurobiology · 2023Review
- The Role and Interactions of Programmed Cell Death 4 and its Regulation by microRNA in Transformed Cells of the Gastrointestinal Tract.Frontiers in oncology · 2022Review
- Hepatoma-Derived Growth Factor: An Overview and Its Role as a Potential Therapeutic Target Molecule for Digestive Malignancies.International journal of molecular sciences · 2020Review
- MicroRNA-95-3p inhibits cell proliferation and metastasis in colorectal carcinoma by HDGF.Biomedical journal · 2020Article
- Stoichiogenomics reveal oxygen usage bias, key proteins and pathways associated with stomach cancer.Scientific reports · 2019Article
- Expression of miR-141 and YAP1 in gastric carcinoma and modulation of cancer cell proliferation and apoptosis.International journal of clinical and experimental pathology · 2019Article
- miR‑141 inhibits glioma vasculogenic mimicry by controlling EphA2 expression.Molecular medicine reports · 2018Article
- miR-141-3p functions as a tumor suppressor modulating activating transcription factor 5 in glioma.Biochemical and biophysical research communications · 2017Article
- miR-326 Inhibits Gastric Cancer Cell Growth Through Downregulating NOB1.Oncology research · 2017Article
- MicroRNA-195 inhibits the behavior of cervical cancer tumors by directly targeting HDGF.Oncology letters · 2017Article
- TRPV4 plays a role in breast cancer cell migration via CaOncogenesis · 2017Article
- Hepatoma-derived growth factor: A survival-related protein in prostate oncogenesis and a potential target for vitamin K2.Urologic oncology · 2016Article
- Anti-proliferative role and prognostic implication of miR-141 in gastric cancer.American journal of translational research · 2016Article
- Recent advances in the molecular diagnostics of gastric cancer.World journal of gastroenterology · 2015Review
- MicroRNA-141 inhibits migration of gastric cancer by targeting zinc finger E-box-binding homeobox 2.Molecular medicine reports · 2015Article
- Hepatoma-Derived Growth Factor: Its Possible Involvement in the Progression of Hepatocellular Carcinoma.International journal of molecular sciences · 2015Review
- MicroRNA-141 inhibits tumor growth and metastasis in gastric cancer by directly targeting transcriptional co-activator with PDZ-binding motif, TAZ.Cell death & disease · 2015Article
- Hepatoma-derived growth factor predicts unfavorable prognosis of epithelial ovarian cancer.OncoTargets and therapy · 2015Article
- miR-141 suppresses the growth and metastasis of HCC cells by targeting E2F3.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
miR-141 belongs to the miR-200 family, and has been found to be associated with numerous human malignancies; however, its role in gastric cancer (GC) has not been examined in detail. Here, we validated that miR-141 was decreased in GC tissues and cell lines. Forced expression of miR-141 significantly repressed GC cell proliferation and colony formation. Furthermore, miR-141 suppressed in vitro migration and invasion of GC cells. Hepatoma-derived growth factor (HDGF) was confirmed to be a direct target of miR-141 in GC cells. The suppressive effects of miR-141 on GC cell proliferation, colony formation, in vitro migration, and invasion were partially mediated by suppressing HDGF expression. Moreover, the expression of HDGF was negatively correlated with miR-141 in GC tissues. Our data suggest that miR-141 might be associated and plays essential role in GC progression.
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