Evidence map›Paper›PMID 24276343›Full record

SynthesisJAMA pediatrics2014

Barriers to human papillomavirus vaccination among US adolescents: a systematic review of the literature.

Dawn M Holman, Vicki Benard, Katherine B Roland, Meg Watson, Nicole Liddon, Shannon Stokley

6 registry-linked trialsOpen access · greenAbstract readSystematic Review
In one paragraph

Synthesis in JAMA pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 513 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
513citing papers in PubMed, 7 pooled it
39.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02546752 early_phase1completednot on this mapstarted 2015, after this paper: background citation

Use of a Patient Education/Messaging Platform to Increase Uptake and Series Completion of the HPV Vaccine

TypeinterventionalSponsorRegenstrief Institute, Inc.Ran2015 to 2016Enrolled1,306ConditionsHuman Papilloma Virus Infection Type 11, Human Papilloma Virus Infection Type 16, Human Papilloma Virus Infection Type 18, Human Papilloma Virus Infection Type 6ArmsTHEO
NCT03510091 nacompletednot on this mapstarted 2018, after this paper: background citation

Video-assisted Counseling for Human Papillomavirus Vaccination: A Pilot Study

TypeinterventionalSponsorLe Bonheur Children's HospitalRan2018 to 2019Enrolled21ConditionsHuman Papillomavirus InfectionArmsCounseling
NCT06290206 nacompletednot on this mapstarted 2024, after this paper: background citation

PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - BootCamp Translation

TypeinterventionalSponsorUniversity of UtahRan2024 to 2024Enrolled18ConditionsHPV Vaccination, Vaccine, Uptake, VaccinationArmsPREVENT - BCT
NCT06738355 nacompletednot on this mapstarted 2025, after this paper: background citation

PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - Pilot Trial

TypeinterventionalSponsorUniversity of UtahRan2025 to 2025Enrolled335ConditionsHPV Vaccination, Uptake Vaccination, Series CompletionArmsPREVENT
NCT07217145 phase3active not recruitingnot on this mapstarted 2025, after this paper: background citation

PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - Randomized Controlled Trial (RCT)

TypeinterventionalSponsorUniversity of UtahRan2025 to 2027Enrolled1,455ConditionsHPV Vaccination, Uptake Vaccination, Series CompletionArmsPREVENT
NCT07521163 nacompletednot on this mapstarted 2026, after this paper: background citation

Effect of a Health Belief Model Based Education Program on Women's Cervical Cancer Knowledge and HPV Vaccination Attitudes in Primary Care Settings: A Quasi-Experimental Pre-test-Posttest Controlled Study

TypeinterventionalSponsorMuhammet Faruk YigitRan2026 to 2026Enrolled154ConditionsCervical Cancer, Human Papillomavirus Infection, Preventive Health ServicesArmsHealth Belief Model-Based Education
3 · Its place in the literature

Who cites it

513 citing papers in PubMed, 7 syntheses or guidelines pooled it, 849 citations in OpenAlex.

  1. Pooled it
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  6. Disparities in Healthcare Providers' Recommendation of HPV Vaccination for U.S. Adolescents: A Systematic Review.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Pooled it
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  19. Factors Associated with HPV Vaccination Among Japanese Women: A Cross-Sectional Study Using the 7 C Vaccination Readiness Model.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
  20. Article

453 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dawn M HolmanDivision of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Vicki BenardDivision of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Katherine B RolandDivision of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Meg WatsonDivision of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Nicole LiddonDivision of Sexually Transmitted Disease Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.
Shannon StokleyImmunization Services Division, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, Georgia.
National Center for Chronic Disease Prevention and Health Promotion · USCenters for Disease Control and Prevention · USNational Center for Immunization and Respiratory Diseases · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

importanceSince licensure of the human papillomavirus (HPV) vaccine in 2006, HPV vaccine coverage among US adolescents has increased but remains low compared with other recommended vaccines.

objectiveTo systematically review the literature on barriers to HPV vaccination among US adolescents to inform future efforts to increase HPV vaccine coverage. EVIDENCE REVIEW: We searched PubMed and previous review articles to identify original research articles describing barriers to HPV vaccine initiation and completion among US adolescents. Only articles reporting data collected in 2009 or later were included. Findings from 55 relevant articles were summarized by target populations: health care professionals, parents, underserved and disadvantaged populations, and males.

findingsHealth care professionals cited financial concerns and parental attitudes and concerns as barriers to providing the HPV vaccine to patients. Parents often reported needing more information before vaccinating their children. Concerns about the vaccine's effect on sexual behavior, low perceived risk of HPV infection, social influences, irregular preventive care, and vaccine cost were also identified as potential barriers among parents. Some parents of sons reported not vaccinating their sons because of the perceived lack of direct benefit. Parents consistently cited health care professional recommendations as one of the most important factors in their decision to vaccinate their children. CONCLUSIONS AND RELEVANCE: Continued efforts are needed to ensure that health care professionals and parents understand the importance of vaccinating adolescents before they become sexually active. Health care professionals may benefit from guidance on communicating HPV recommendations to patients and parents. Further efforts are also needed to reduce missed opportunities for HPV vaccination when adolescents interface with the health care system. Efforts to increase uptake should take into account the specific needs of subgroups within the population. Efforts that address system-level barriers to vaccination may help to increase overall HPV vaccine uptake.

Indexed as

Attitude of Health PersonnelHealth Services AccessibilityAdolescentFemaleHealth Knowledge, Attitudes, PracticeHumansMalePapillomavirus InfectionsPapillomavirus VaccinesParentsPatient Acceptance of Health CareUterine Cervical NeoplasmsVaccinationPapillomavirus Vaccines

Identifiers

PMID24276343
PMCPMC4538997
OpenAlexW2167279119

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.