Evidence map›Paper›PMID 24274754›Full record

ReviewAnnual review of genetics2013

RNase III: Genetics and function; structure and mechanism.

Donald L Court, Jianhua Gan, Yu-He Liang, Gary X Shaw, Joseph E Tropea, Nina Costantino, David S Waugh, Xinhua Ji

Open access · bronzeAbstract readReview
In one paragraph

Review in Annual review of genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 184 citations in OpenAlex.

  1. Article
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  4. HnRNP C binding to invertedScience advances · 2026
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  10. The NagY antiterminator inMicrobiology spectrum · 2025
    Article
  11. RiboCop surveils pre-rRNA processing by Dicer in cellular quiescence.bioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
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48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Donald L CourtCenter for Cancer Research, National Cancer Institute, Frederick, Maryland 21702; email: courtd@mail.nih.gov , ganj@mail.nih.gov , liangyh@mail.nih.gov , shawg@mail.nih.gov , costantn@mail.nih.gov , tropeajo@mail.nih.gov , waughd@mail.nih.gov , jix@mail.nih.gov.
Jianhua Gan
Yu-He Liang
Gary X Shaw
Joseph E Tropea
Nina Costantino
David S Waugh
Xinhua Ji
Center for Cancer Research · USFudan University · CNNational Cancer Institute · USUniversity of Pittsburgh · US

Funding

Biomolecular Structure and Mechanism, Structure-Based Drug DesignZIABC010326 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI JI, XINHUA · 2009 to 2024
$27.3M
Structural of Biomolecular Systems by X Ray DiffractionZ01BC010326 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI JI, XINHUA · 2000 to 2008
$2.6M
Intramural NIH HHS Z01 BC010326
6 · The paper itself

Abstract

RNase III is a global regulator of gene expression in Escherichia coli that is instrumental in the maturation of ribosomal and other structural RNAs. We examine here how RNase III itself is regulated in response to growth and other environmental changes encountered by the cell and how, by binding or processing double-stranded RNA (dsRNA) intermediates, RNase III controls the expression of genes. Recent insight into the mechanism of dsRNA binding and processing, gained from structural studies of RNase III, is reviewed. Structural studies also reveal new cleavage sites in the enzyme that can generate longer 3' overhangs.

Indexed as

3' Untranslated Regions5' Untranslated RegionsAmino Acid MotifsBacteriophage lambdaCatalysisClustered Regularly Interspaced Short Palindromic RepeatsEscherichia coliEscherichia coli ProteinsEukaryotic CellsGene Expression Regulation, BacterialNucleic Acid ConformationOperonProkaryotic CellsProtein Processing, Post-TranslationalRibonuclease IIIRNA3' Untranslated Regions5' Untranslated RegionsEscherichia coli ProteinsRibonuclease IIIRNARNA, BacterialRNA, Double-StrandedRNA, RibosomalRNA, Small Untranslated

Identifiers

PMID24274754
PMCPMC6311387
OpenAlexW2112732905

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.