ReviewAnnual review of physiology2014
Feed your head: neurodevelopmental control of feeding and metabolism.
Review in Annual review of physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Adenosine transmission from hypothalamic tanycytes to AGRP/NPY neurons regulates energy homeostasis.Experimental & molecular medicine · 2025Article
- Effects of Exogenous Glucocorticoid Infusion on Appetitic Center Development in Postnatal Dairy Bull Calves.Animals : an open access journal from MDPI · 2023Article
- Does EGFR Signaling Mediate Orexin System Activity in Sleep Initiation?International journal of molecular sciences · 2023Review
- SHH and Notch regulate SOX9+ progenitors to govern arcuate POMC neurogenesis.Frontiers in neuroscience · 2022Article
- Evolutionarily conserved regulation of sleep by epidermal growth factor receptor signaling.Science advances · 2019Article
- The parental brain and behavior: A target for endocrine disruption.Frontiers in neuroendocrinology · 2019Review
- Rictor/TORC2 mediates gut-to-brain signaling in the regulation of phenotypic plasticity in C. elegans.PLoS genetics · 2018Article
- Caffeine inhibits hypothalamic ANature communications · 2017Article
- Leptin Induces Mitosis and Activates the Canonical Wnt/β-Catenin Signaling Pathway in Neurogenic Regions ofFrontiers in endocrinology · 2017Article
- C. elegans Stress-Induced Sleep Emerges from the Collective Action of Multiple Neuropeptides.Current biology : CB · 2016Article
- Developmental specification of metabolic circuitry.Frontiers in neuroendocrinology · 2015Review
- Hypothalamic Non-AgRP, Non-POMC GABAergic Neurons Are Required for Postweaning Feeding and NPY Hyperphagia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Specification of select hypothalamic circuits and innate behaviors by the embryonic patterning gene dbx1.Neuron · 2015Article
- Hypothalamic tanycytes-masters and servants of metabolic, neuroendocrine, and neurogenic functions.Frontiers in neuroscience · 2015Review
- The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice.Frontiers in neuroscience · 2014Article
- Patterning, specification, and differentiation in the developing hypothalamus.Wiley interdisciplinary reviews. Developmental biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
During critical periods of development early in life, excessive or scarce nutritional environments can disrupt the development of central feeding and metabolic neural circuitry, leading to obesity and metabolic disorders in adulthood. A better understanding of the genetic networks that control the development of feeding and metabolic neural circuits, along with knowledge of how and where dietary signals disrupt this process, can serve as the basis for future therapies aimed at reversing the public health crisis that is now building as a result of the global obesity epidemic. This review of animal and human studies highlights recent insights into the molecular mechanisms that regulate the development of central feeding circuitries, the mechanisms by which gestational and early postnatal nutritional status affects this process, and approaches aimed at counteracting the deleterious effects of early over- and underfeeding.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.