Evidence map›Paper›PMID 24273740›Full record

ArticleQuantitative imaging in medicine and surgery2013

Changes in cochlear blood flow in mice due to loud sound exposure measured with Doppler optical microangiography and laser Doppler flowmetry.

Roberto Reif, Zhongwei Zhi, Suzan Dziennis, Alfred L Nuttall, Ruikang K Wang

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Robust principal component analysis in optical micro-angiography.Quantitative imaging in medicine and surgery · 2017
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Roberto ReifUniversity of Washington, Department of Bioengineering, Seattle, WA 98195, USA;
Zhongwei Zhi
Suzan Dziennis
Alfred L Nuttall
Ruikang K Wang

Funding

PORTLAND AREA COMMUNICATION RESEARCH CORE CENTERP30DC005983 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI NUTTALL, ALFRED L · 2003 to 2017
$9.0M
CONTROL OF INNER EAR MICROCIRULATIONR01DC000105 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NUTTALL, ALFRED L · 1989 to 2017
$7.6M
Volumetric imaging of blood perfusion and tissue morphology in the cochleaR01DC010201 · NIDCD · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2009 to 2013
$2.2M
NIDCD NIH HHS P30 DC005983NIDCD NIH HHS R01 DC000105NIDCD NIH HHS R01 DC010201
6 · The paper itself

Abstract

In this work we determined the contributions of loud sound exposure (LSE) on cochlear blood flow (CoBF) in an in vivo anesthetized mouse model. A broadband noise system (20 kHz bandwidth) with an intensity of 119 dB SPL, was used for a period of one hour to produce a loud sound stimulus. Two techniques were used to study the changes in blood flow, a Doppler optical microangiography (DOMAG) system; which can measure the blood flow within individual cochlear vessels, and a laser Doppler flowmetry (LDF) system; which averages the blood flow within a volume (a hemisphere of ~1.5 mm radius) of tissue. Both systems determined that the blood flow within the cochlea is reduced due to the LSE stimulation.

Indexed as

Cochlear blood flow (CoBF)Doppler optical microangiography (DOMAG)hypoxia

Identifiers

PMID24273740
PMCPMC3834207

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.