ArticleNeuroImage. Clinical2013
The brains of high functioning autistic individuals do not synchronize with those of others.
Article in NeuroImage. Clinical, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Naturalistic stimuli in neuroimaging studies of autism spectrum disorder: a systematic review.Frontiers in human neuroscience · 2026Pooled it
- Article
- Phase synchronization modes are associated with heterogeneous social orienting in children and adolescents with autism.Molecular autism · 2026Article
- Inter-subject correlations and their behavioral associations vary across movies: Implications for generalizability.bioRxiv : the preprint server for biology · 2026Article
- Temporally-resolved deep learning reveals autism symptom-specific neural signatures during naturalistic social experiences.Research square · 2026Article
- Brain idiosyncrasy during biological-motion perception is amplified in autistic individuals with intellectual impairment.Journal of neurodevelopmental disorders · 2026Article
- Pregistered movie-fMRI analyses reveal altered visual feature encoding in autism in pSTS.bioRxiv : the preprint server for biology · 2026Article
- Functional changes of precuneus architecture across newborns, infants, and early adolescents.Scientific reports · 2026Article
- Reduced inter-subject functional connectivity during movies in autism: replicability across cross-national fMRI datasets.Molecular autism · 2026Article
- Trait psychoticism is associated with greater intersubject neural dissimilarity during naturalistic social movie viewing.Scientific reports · 2026Article
- Alterations in self-related brain networks in autism spectrum disorder: a systematic review of functional and structural magnetic resonance imaging studies.Psychoradiology · 2026Review
- Children with Autism Show Impaired Oculomotor Entrainment to Predictable Stimuli.bioRxiv : the preprint server for biology · 2025Article
- Social inference brain networks in autistic adults during movie-viewing: functional specialization and heterogeneity.Molecular autism · 2025Article
- Shared orbitofrontal dynamics to a drug-themed movie track craving and recovery in heroin addiction.Brain : a journal of neurology · 2025Article
- Disentangling the Switching Behavior in Functional Connectivity Dynamics in Autism Spectrum Disorder: Insights from Developmental Cohort Analysis and Molecular-Cellular Associations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Neural similarity and interaction success in autistic and non-autistic adolescents.Scientific reports · 2025Article
- Real-world goal-directed behavior reveals aberrant functional brain connectivity in children with ADHD.PloS one · 2025Article
- Can similarity of autistic traits promote neural synchronization?Experimental brain research · 2024Article
- Inter-subject gamma oscillation synchronization as a biomarker of abnormal processing of social interaction in ADHD.Scientific reports · 2024Article
- Naturalistic drug cue reactivity in heroin use disorder: orbitofrontal synchronization as a marker of craving and recovery.medRxiv : the preprint server for health sciences · 2024Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multifaceted and idiosyncratic aberrancies in social cognition characterize autism spectrum disorders (ASDs). To advance understanding of underlying neural mechanisms, we measured brain hemodynamic activity with functional magnetic resonance imaging (fMRI) in individuals with ASD and matched-pair neurotypical (NT) controls while they were viewing a feature film portraying social interactions. Pearson's correlation coefficient was used as a measure of voxelwise similarity of brain activity (InterSubject Correlations-ISCs). Individuals with ASD showed lower ISC than NT controls in brain regions implicated in processing social information including the insula, posterior and anterior cingulate cortex, caudate nucleus, precuneus, lateral occipital cortex, and supramarginal gyrus. Curiously, also within NT group, autism-quotient scores predicted ISC in overlapping areas, including, e.g., supramarginal gyrus and precuneus. In ASD participants, functional connectivity was decreased between the frontal pole and the superior frontal gyrus, angular gyrus, superior parietal lobule, precentral gyrus, precuneus, and anterior/posterior cingulate gyrus. Taken together these results suggest that ISC and functional connectivity measure distinct features of atypical brain function in high-functioning autistic individuals during free viewing of acted social interactions. Our ISC results suggest that the minds of ASD individuals do not 'tick together' with others while perceiving identical dynamic social interactions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.