Evidence map›Paper›PMID 24273590›Full record

ArticleSoft matter2013

Using Small-Angle Scattering Techniques to Understand Mechanical Properties of Biopolymer-Based Biomaterials.

Laura L Hyland, Marc B Taraban, Y Bruce Yu

Abstract read
In one paragraph

Article in Soft matter, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laura L HylandFischell Department of Bioengineering, University of Maryland, College Park, MD, USA. ; Tel: 301-405-2829.
Marc B Taraban
Y Bruce Yu

Funding

Engineering Peptide-based BiomaterialsR01EB004416 · NIBIB · UNIVERSITY OF UTAH · PI YU, YIHUA BRUCE · 2004 to 2010
$2.7M
Novel Fluorophores for Molecular and Cellular ImagingR01EB012003 · NIBIB · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI GRYCZYNSKI, ZYGMUNT, YU, YIHUA BRUCE · 2011 to 2014
$1.8M
NIBIB NIH HHS R01 EB004416NIBIB NIH HHS R01 EB012003
6 · The paper itself

Abstract

The design and engineering of innovative biopolymer-based biomaterials for a variety of biomedical applications should be based on the understanding of the relationship between their nanoscale structure and mechanical properties. Down the road, such understanding could be fundamental to tune the properties of engineered tissues, extracellular matrices for cell delivery and proliferation/differentiation, etc. In this tutorial review, we attempt to show in what way biomaterial structural data can help to understand the bulk material properties. We begin with some background on common types of biopolymers used in biomaterials research, discuss some typical mechanical testing techniques and then review how others in the field of biomaterials have utilized small-angle scattering for material characterization. Detailed examples are then used to show the full range of possible characterization techniques available for biopolymer-based biomaterials. Future developments in the area of material characterization by small-angle scattering will undoubtedly facilitate the use of structural data to control the kinetics of assembly and final properties of prospective biomaterials.

Identifiers

PMID24273590
PMCPMC3835338

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.