ReviewOncoTargets and therapy2013
Exploring and exploiting the fundamental role of microRNAs in tumor pathogenesis.
Review in OncoTargets and therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- The role of tumor microenvironment and self-organization in cancer progression: Key insights for therapeutic development.BioImpacts : BI · 2025Review
- Prediction methods for microRNA targets in bilaterian animals: Toward a better understanding by biologists.Computational and structural biotechnology journal · 2021Review
- The emerging roles of exosomal miRNAs in nasopharyngeal carcinoma.American journal of cancer research · 2021Review
- MicroRNA‑128‑b regulates epidermal growth factor receptor expression in non‑small cell lung cancer.Molecular medicine reports · 2019Article
- Plasma expression of miRNA-21, - 214, -34a, and -200a in patients with persistent HPV infection and cervical lesions.BMC cancer · 2019Article
- A Potential Prognostic Gene Signature for Predicting Survival for Glioblastoma Patients.BioMed research international · 2019Article
- Resveratrol Inhibits Proliferation in HBL-52 Meningioma Cells.OncoTargets and therapy · 2019Article
- Model based on GA and DNN for prediction of mRNA-Smad7 expression regulated by miRNAs in breast cancer.Theoretical biology & medical modelling · 2018Article
- Article
- Human papillomavirus E6 and E7 oncoproteins affect the expression of cancer-related microRNAs: additional evidence in HPV-induced tumorigenesis.Journal of cancer research and clinical oncology · 2016Article
- MicroRNA-200b Impacts Breast Cancer Cell Migration and Invasion by Regulating Ezrin-Radixin-Moesin.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
- Article
- Increased risk of tumor in DM1 is not related to exposure to common lifestyle risk factors.Journal of neurology · 2016Article
- Circulating miR-106a is a Novel Prognostic and Lymph Node Metastasis Indicator for Cholangiocarcinoma.Scientific reports · 2015Article
- Mechanisms of Invasion in Head and Neck Cancer.Archives of pathology & laboratory medicine · 2015Review
- Posttranscriptional deregulation of signaling pathways in meningioma subtypes by differential expression of miRNAs.Neuro-oncology · 2015Article
- Structure and function of Gab2 and its role in cancer (Review).Molecular medicine reports · 2015Review
- Effect of microRNA-203 on tumor growth in human hypopharyngeal squamous cell carcinoma.Molecular and cellular biochemistry · 2015Article
- Overexpression of miR‑145 in U87 cells reduces glioma cell malignant phenotype and promotes survival after in vivo implantation.International journal of oncology · 2015Article
- MicroRNAs are potential prognostic and therapeutic targets in diabetic osteoarthritis.Journal of bone and mineral metabolism · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
miRNAs (miRs) are short RNA molecules that are involved in the posttranscriptional regulation of mRNA. The roles of miRs in tumor pathogenesis have only recently become a focus of research. It is becoming increasingly clear that miRs are important regulators of apoptosis, proliferation, invasion, and metastasis in cancer cells during cancer genesis and progression, furthering our understanding of cancer. In the present review, we summarize and evaluate the recent advances in our understanding of the characteristics of miRs as well as their regulated functions in cancer stem cells (CSCs), the epithelial-mesenchymal transition (EMT), and the tumor microenvironment (TM), describing their roles in tumor pathogenesis and their possible use as new therapeutic targets and biomarkers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.