ArticleGenome biology and evolution2013
The complex intron landscape and massive intron invasion in a picoeukaryote provides insights into intron evolution.
Article in Genome biology and evolution, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 37 citations in OpenAlex.
- Horizontal transmission of functionally diverse transposons is a major source of new introns.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Transposable elements drive intron gain in diverse eukaryotes.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Intron losses and gains in the nematodes.Biology direct · 2022Article
- Internally Symmetrical Stwintrons and Related Canonical Introns in Hypoxylaceae Species.Journal of fungi (Basel, Switzerland) · 2021Article
- Review
- The emergence and evolution of intron-poor and intronless genes in intron-rich plant gene families.The Plant journal : for cell and molecular biology · 2021Article
- Genome Resolved Biogeography of Mamiellales.Genes · 2020Article
- Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome.PLoS genetics · 2019Article
- Origin and Spread of Spliceosomal Introns: Insights from the Fungal Clade Zymoseptoria.Genome biology and evolution · 2017Article
- Article
- mdRNA-Seq analysis of marine microbial communities from the northern Red Sea.Scientific reports · 2016Article
- Evidence-based green algal genomics reveals marine diversity and ancestral characteristics of land plants.BMC genomics · 2016Article
- Article
- Evaluation of the mechanisms of intron loss and gain in the social amoebae Dictyostelium.BMC evolutionary biology · 2015Article
- Intron Invasions Trace Algal Speciation and Reveal Nearly Identical Arctic and Antarctic Micromonas Populations.Molecular biology and evolution · 2015Article
- Article
- Novel Introner-Like Elements in fungi Are Involved in Parallel Gains of Spliceosomal Introns.PloS one · 2015Article
- Recurrent loss of specific introns during angiosperm evolution.PLoS genetics · 2014Article
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Authors and funding
3 authors at 1 institution in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Genes in pieces and spliceosomal introns are a landmark of eukaryotes, with intron invasion usually assumed to have happened early on in evolution. Here, we analyze the intron landscape of Micromonas, a unicellular green alga in the Mamiellophyceae lineage, demonstrating the coexistence of several classes of introns and the occurrence of recent massive intron invasion. This study focuses on two strains, CCMP1545 and RCC299, and their related individuals from ocean samplings, showing that they not only harbor different classes of introns depending on their location in the genome, as for other Mamiellophyceae, but also uniquely carry several classes of repeat introns. These introns, dubbed introner elements (IEs), are found at novel positions in genes and have conserved sequences, contrary to canonical introns. This IE invasion has a huge impact on the genome, doubling the number of introns in the CCMP1545 strain. We hypothesize that each IE class originated from a single ancestral IE that has been colonizing the genome after strain divergence by inserting copies of itself into genes by intron transposition, likely involving reverse splicing. Along with similar cases recently observed in other organisms, our observations in Micromonas strains shed a new light on the evolution of introns, suggesting that intron gain is more widespread than previously thought.
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