ArticleThe Journal of infectious diseases2014
Selected vaginal bacteria and risk of preterm birth: an ecological perspective.
Article in The Journal of infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Gut microbiota phenotypes of obesity.NPJ biofilms and microbiomesPooled it
- Effects of emergency/nonemergency cervical cerclage on the vaginal microbiome of pregnant women with cervical incompetence.Frontiers in cellular and infection microbiology · 2023Trial
- Effects of Dietary Quality on Vaginal Microbiome Composition Throughout Pregnancy in a Multi-Ethnic Cohort.Nutrients · 2024Article
- A systematic review and guide for using multi-response statistical models in co-infection research.Royal Society open science · 2024Article
- Molecular Mechanism of Microbiota Metabolites in Preterm Birth: Pathological and Therapeutic Insights.International journal of molecular sciences · 2021Review
- Explaining the Black-White Disparity in Preterm Birth: A Consensus Statement From a Multi-Disciplinary Scientific Work Group Convened by the March of Dimes.Frontiers in reproductive health · 2021Review
- Vaginal Microbiome Composition in Early Pregnancy and Risk of Spontaneous Preterm and Early Term Birth Among African American Women.Frontiers in cellular and infection microbiology · 2021Article
- Maternal genitourinary infections and poor nutritional status increase risk of preterm birth in Gasabo District, Rwanda: a prospective, longitudinal, cohort study.BMC pregnancy and childbirth · 2020Article
- Profiles of the bacterial community in short-term indwelling urinary catheters by duration of catheterization and subsequent urinary tract infection.American journal of infection control · 2020Article
- Comparison of the Genital Microbiomes of Pregnant Aboriginal and Non-aboriginal Women.Frontiers in cellular and infection microbiology · 2020Article
- Exploring profile and potential influencers of vaginal microbiome among asymptomatic pregnant Chinese women.PeerJ · 2019Article
- Article
- First Trimester Levels of BV-Associated Bacteria and Risk of Miscarriage Among Women Early in Pregnancy.Maternal and child health journal · 2015Article
- Identification of a gene in Mycoplasma hominis associated with preterm birth and microbial burden in intraamniotic infection.American journal of obstetrics and gynecology · 2015Article
- Persistent microbial dysbiosis in preterm premature rupture of membranes from onset until delivery.PeerJ · 2015Article
- Vaginitis in pregnancy is related to adverse perinatal outcome.Pakistan journal of medical sciences · 2015Article
- Is there a role for probiotics in the prevention of preterm birth?Frontiers in immunology · 2015Review
- Epidemiologic factors and urogenital infections associated with preterm birth in a midwestern U.S. population.Obstetrics and gynecology · 2014Article
- Mycoplasma, bacterial vaginosis-associated bacteria BVAB3, race, and risk of preterm birth in a high-risk cohort.American journal of obstetrics and gynecology · 2014Article
- The vaginal microbiota of pregnant women who subsequently have spontaneous preterm labor and delivery and those with a normal delivery at term.Microbiome · 2014Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
We examined the community ecology of vaginal microbial samples taken from pregnant women with previous preterm birth experience to investigate whether targeted pathogenic and commensal bacteria are related to risk of preterm birth in the current pregnancy. We found a significant correlation between the community structure of selected bacteria and birth outcome, but the correlation differed among self-reported racial/ethnic groups. Using a community ordination analysis, we observed infrequent co-occurrence of Mycoplasma and bacteria vaginosis associated bacteria 3 (BVAB3) among black and Hispanic participants. In addition, we found that the vaginal bacteria responded differently in different racial/ethnic groups to modifications of maternal behavioral (ie, douching and smoking) and biological traits (ie, body mass index [BMI]). Even after accounting for these maternal behaviors and traits, the selected vaginal bacteria was significantly associated with preterm birth among black and Hispanic participants. By contrast, white participants did not exhibit significant correlation between microbial community and birth outcome. Findings from this study affirm the necessity of considering women's race/ethnicity when evaluating the correlation between vaginal bacteria and preterm birth. The study also illustrates the importance of studying the vaginal microbiota from an ecological perspective, and demonstrates the power of ecological community analysis to improve understanding of infectious disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.