Evidence map›Paper›PMID 24272069›Full record

ReviewCurrent HIV/AIDS reports2013

Treatment of genotype 1 HCV infection in the HIV coinfected patient in 2014.

Cody A Chastain, Susanna Naggie

Abstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Hepatitis C.Lancet (London, England) · 2015
    Review
  6. Sofosbuvir, a New Nucleotide Analogue, for the Treatment of Chronic Hepatitis C Infection.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2015
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Cody A ChastainDivision of Infectious Diseases, Vanderbilt University Medical Center, A-2200 MCN, 1161 21st Avenue, Nashville, TN, 37232-2582, USA, cody.a.chastain@vanderbilt.edu.
Susanna Naggie

Funding

Moving Towards More Individualized Therapies in HIV/HCV Co-infected PatientsK23AI096913 · NIAID · DUKE UNIVERSITY · PI NAGGIE, SUSANNA · 2011 to 2014
$355k
NIAID NIH HHS K23 AI096913
6 · The paper itself

Abstract

Hepatitis C (HCV) coinfection is the leading cause of liver-related morbidity and is a leading cause of mortality in human immunodeficiency virus (HIV)-infected individuals in the antiretroviral therapy era. Direct-acting antiviral (DAA) therapies are transforming how HCV is treated with significant improvements in efficacy and tolerability. In this article, DAA agents expected to be available in 2014 are reviewed, including telaprevir, boceprevir, sofosbuvir, simeprevir, faldaprevir, and daclatasvir. Available data regarding clinical efficacy, adverse effects, and drug interactions in HIV-HCV coinfection are discussed. The management of adverse effects of HCV therapy and treatment considerations in patients with cirrhosis are also reviewed.

Indexed as

Antiretroviral Therapy, Highly ActiveAntiviral AgentsClinical Trials as TopicCoinfectionDrug Therapy, CombinationGenotypeHepacivirusHepatitis C, ChronicHIV InfectionsHumansPractice Guidelines as TopicAntiviral Agents

Identifiers

PMID24272069
PMCPMC4892376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.