ArticleClinical research in cardiology : official journal of the German Cardiac Society2014
Admission glucose, fasting glucose, HbA1c levels and the SYNTAX score in non-diabetic patients undergoing coronary angiography.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03700645 (Allopurinol in the Treatment of Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease Treated by Either PCI or CABG), which is not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Allopurinol in the Treatment of Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease Treated by Either PCI or CABG: Pilot Study
Who cites it
14 citing papers in PubMed, 48 citations in OpenAlex.
- Different levels of lipids, Hb1Ac and cytokines among patients with coronary artery disease.Heliyon · 2024Article
- Association of the stress hyperglycemia ratio with coronary artery disease complexity as assessed by the SYNTAX score in patients with acute coronary syndrome.Diabetology & metabolic syndrome · 2024Article
- Relationship between the triglyceride-glucose index and the SYNTAX score 2 in patients with non-ST elevation myocardial infarction.Cardiovascular endocrinology & metabolism · 2023Article
- Hemoglobin A1c and Angiographic Severity with Coronary Artery Disease: A Cross-Sectional Study.International journal of general medicine · 2022Article
- Determinants of Longitudinal Change of Glycated Hemoglobin in a Large Non-Diabetic Population.Journal of personalized medicine · 2021Article
- Elevated glycosylated hemoglobin levels and their interactive effects on hypertension risk in nondiabetic Chinese population: a cross-sectional survey.BMC cardiovascular disorders · 2020Article
- Article
- Cardiac Gated Computed Tomography Angiography Discloses a Correlation Between the Volumes of All Four Cardiac Chambers and Heart Rate in Men But Not in Women.Women's health reports (New Rochelle, N.Y.) · 2020Article
- Predictive value of fasting blood glucose for serious coronary atherosclerosis in non-diabetic patients.The Journal of international medical research · 2019Article
- An association between volumes of the cardiac chambers and troponin levels in individuals submitted to cardiac coronary computed tomography.Clinical cardiology · 2017Article
- Classical determinants of coronary artery disease as predictors of complexity of coronary lesions, assessed with the SYNTAX score.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2017Article
- Association Between IL-18 and Carotid Intima-Media Thickness in Patients with Type II Diabetic Nephropathy.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- SYNTAX score-0 patients: risk stratification in nonobstructive coronary artery disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Article
- Hyperglycemia in patients referred for cardiac catheterization is associated with preexisting diabetes rather than a stress-related phenomenon: a prospective cross-sectional study.Clinical cardiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPre-diabetic state is a major risk factor for the development of diabetes and cardiovascular events. Admission glucose, fasting glucose and HbA1c levels have an effect on prognosis in patients with pre-diabetes and in non-diabetic individuals. The aim of the present study was to investigate which of the following glucometabolic markers (admission glucose, fasting glucose and HbA1c levels) is correlated with the severity of coronary artery disease (CAD) in non-diabetic patients.
methodsCAD severity according to SYNTAX score was prospectively evaluated in 226 non-diabetic patients hospitalized with myocardial infarction or stable angina and underwent coronary angiography. Glucose intolerance was assessed by serum admission glucose, fasting glucose and HbA1c levels. Logistic regression analysis was used to evaluate which glucometabolic factor has the strongest correlation with CAD severity.
resultsHbA1c was the only glucometabolic factor associated with SYNTAX score above 22 (OR = 3.03, CI 95% 1.03-8.9, p = 0.04). HbA1c was also significantly associated with CAD severity in subgroup analysis (MI and stable angina).
conclusionsIn non-diabetic patients with myocardial infarction or stable angina, HbA1c levels correlate with CAD severity as measured by the SYNTAX score. No correlation was found between admission glucose or fasting glucose levels and CAD severity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.