Evidence map›Paper›PMID 24271347›Full record

Trial reportAIDS and behavior2014

The use of cell phone support for non-adherent HIV-infected youth and young adults: an initial randomized and controlled intervention trial.

Marvin E Belzer, Sylvie Naar-King, Johanna Olson, Moussa Sarr, Sarah Thornton, Shoshana Y Kahana, Aditya H Gaur, Leslie F Clark, Adolescent Medicine Trials Network for HIV/AIDS Interventions

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04241627 (Mobile Health Intervention to Promote Medication Adherence Among Adolescents and Young Adults With Chronic Illness), which is not on this map. Cited by 69 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 15 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04241627 nacompletednot on this mapstarted 2020, after this paper: background citation

Mobile Health Intervention to Promote Medication Adherence Among Adolescents and Young Adults With Chronic Illness

TypeinterventionalSponsorChildren's Hospital Los AngelesRan2020 to 2022Enrolled34ConditionsMedication AdherenceArmsCell Phone Support
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 15 syntheses or guidelines pooled it.

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  15. Interventions to Promote Oral Medication Adherence in the Pediatric Chronic Illness Population: A Systematic Review From the Children's Oncology Group.Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marvin E BelzerDepartment of Pediatrics, Children's Hospital Los Angeles and University of Southern California, 4650 Sunset Blvd MS#2, Los Angels, CA, 90027, USA, mbelzer@chla.usc.edu.
Sylvie Naar-King
Johanna Olson
Moussa Sarr
Sarah Thornton
Shoshana Y Kahana
Aditya H Gaur
Leslie F Clark
Adolescent Medicine Trials Network for HIV/AIDS Interventions

Funding

Adol. Medicine Trials Network for HIV/AIDS InterventionsU01HD040474 · NICHD · WESTAT, INC. · PI HARRIS, DONALD ROBERT · 2001 to 2016
$114.4M
LEADERSHIP GROUP FOR ADOLESCENT MEDICINE TRIALS NETWORKU01HD040533 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILSON, CRAIG M · 2001 to 2016
$76.4M
ZENARESTAT IN DIABETIC NEUROPATHYM01RR005096 · NCRR · TULANE UNIVERSITY OF LOUISIANA · PI FONSECA, VIVIAN A · 1990 to 2006
$17.4M
Adolescent Medicine Trials Network for HIV/AIDS InterventionsU01HD040463 · NICHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI BELZER, MARVIN E · 2001 to 2015
$10.5M
NEW ORLEANS ADOLESCENT MEDICINE TRIALS UNITU01HD040470 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI ABDALIAN, SUE ELLEN · 2001 to 2015
$8.8M
NCRR NIH HHS M01 RR005096NICHD NIH HHS 5U01-HD 40533NICHD NIH HHS 5 UO1 HD 40474NICHD NIH HHS U01 HD040463NICHD NIH HHS U01 HD040470NICHD NIH HHS U01 HD040474NICHD NIH HHS U01 HD040533
6 · The paper itself

Abstract

This randomized behavioral trial examined whether youth living with HIV (YLH) receiving cell-phone support with study funded phone plans, demonstrated improved adherence and viral control during the 24 week intervention and 24 weeks post-intervention compared to controls. Monday through Friday phone calls confirmed medications were taken, provided problem-solving support, and referred to services to address adherence barriers. Of 37 participants (ages 15-24), 62 % were male and 70 % were African American. Self-reported adherence was significantly higher in the intervention group compared to the control at 24 and 48 weeks for the past month (P = 0.007) and log 10 HIV VL was significantly lower at both 24 weeks (2.82 versus 4.52 P = 0.002) and 48 weeks (3.23 versus 4.23 P = 0.043). Adherence and viral load showed medium to large effect sizes across the 48 week study. This is the first study to demonstrate sustained clinically significant reductions in HIV VL using youth friendly technology.

Indexed as

Cell PhoneDrug MonitoringHealth PromotionReminder SystemsAdolescentAnti-HIV AgentsFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansLongitudinal StudiesMaleMedication AdherencePatient CompliancePilot ProjectsSexual BehaviorAnti-HIV Agents

Identifiers

PMID24271347
PMCPMC3962719

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.