ArticleApplied and environmental microbiology2014
Core lipopolysaccharide-specific phage SSU5 as an Auxiliary Component of a Phage Cocktail for Salmonella biocontrol.
Article in Applied and environmental microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Pooled it
- Bacteriophage vB_SalS_KY05 controlsThe veterinary quarterly · 2026Article
- Genomic characterization and phage cocktail suppression of a multidrug-resistantApplied and environmental microbiology · 2026Article
- Sequential receptor engagement dictates the broad host range and fitness trade-offs ofMicrobiology spectrum · 2026Article
- Comparative morphological, genomic, and functional characterization of two newly isolated lytic caudoviricetes phages targeting Escherichia coli and Salmonella.Scientific reports · 2026Article
- Isolation of a complementary bacteriophage from a phage-resistant mutant expands control strategies againstFrontiers in microbiology · 2026Article
- Two receptor-targeting mechanisms of lambda-like siphophage Gifsy-1 of Salmonella Typhimurium.PLoS pathogens · 2025Article
- Amino acid residues in the tail fiber differentiate the host specificity ofJournal of virology · 2025Article
- Precision Phage Cocktail Targeting Surface Appendages for Biocontrol ofAntibiotics (Basel, Switzerland) · 2024Article
- Salmonella enteritidis acquires phage resistance through a point mutation in rfbD but loses some of its environmental adaptability.Veterinary research · 2024Article
- Review
- Multireceptor phage cocktail againstmicroLife · 2024Article
- Characterization and Diversity ofInternational journal of molecular sciences · 2023Article
- Phage Adsorption to Gram-Positive Bacteria.Viruses · 2023Review
- Development of a Bacteriophage Cocktail against Pectobacterium carotovorum Subsp.Applied and environmental microbiology · 2022Article
- A Novel Method to Create Efficient Phage Cocktails via Use of Phage-Resistant Bacteria.Applied and environmental microbiology · 2022Article
- Combination of pre-adapted bacteriophage therapy and antibiotics for treatment of fracture-related infection due to pandrug-resistant Klebsiella pneumoniae.Nature communications · 2022Article
- A review of food additives to control the proliferation and transmission of pathogenic microorganisms with emphasis on applications to raw meat-based diets for companion animals.Frontiers in veterinary science · 2022Review
- Article
- Bacteria have numerous distinctive groups of phage-plasmids with conserved phage and variable plasmid gene repertoires.Nucleic acids research · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salmonella spp. are among the major food-borne pathogens that cause mild diarrhea to severe bacteremia. The use of bacteriophages to control various food-borne pathogens, including Salmonella, has emerged as a promising alternative to traditional chemotherapy. We isolated the Siphoviridae family phage SSU5, which can infect only rough strains of Salmonella. The blocking of SSU5 adsorption by periodate treatment of host Salmonella cells and spotting and adsorption assays with mutants that contain various truncations in their lipopolysaccharide (LPS) cores revealed that the outer core region of the LPS is a receptor of SSU5. SSU5 could infect O-antigen (O-Ag)-deficient Salmonella mutants that developed by challenging of O-Ag-specific phages, and consequently, it delayed the emergence of the phage-resistant Salmonella population in broth culture when treated together with phages using O-Ag as a receptor. Therefore, these results suggested that phage SSU5 would be a promising auxiliary component of a phage cocktail to control rough strains of Salmonella enterica serovar Typhimurium, which might emerge as resistant mutants upon infection by phages using O-Ag as a receptor.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.