ArticleIEEE transactions on bio-medical engineering2013
An interferometric reflectance imaging sensor for point of care viral diagnostics.
Article in IEEE transactions on bio-medical engineering, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Portable Fluorescence Microarray Reader-Enabled Biomarker Panel Detection System for Point-of-Care Diagnosis of Lupus Nephritis.Micromachines · 2025Article
- Highly-Sensitive, Label-Free Detection of Microorganisms and Viruses via Interferometric Reflectance Imaging Sensor.Micromachines · 2023Review
- Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis.Biosensors · 2023Review
- A critical review: Recent advances in "digital" biomolecule detection with single copy sensitivity.Biosensors & bioelectronics · 2021Review
- Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single-particle analysis platforms.Journal of extracellular vesicles · 2021Article
- Label-free tomography of living cellular nanoarchitecture using hyperspectral self-interference microscopy.Biomedical optics express · 2019Article
- Advances in automated tongue diagnosis techniques.Integrative medicine research · 2019Review
- Article
- Interferometric Reflectance Imaging Sensor (IRIS)--A Platform Technology for Multiplexed Diagnostics and Digital Detection.Sensors (Basel, Switzerland) · 2015Review
- Democratization of Nanoscale Imaging and Sensing Tools Using Photonics.Analytical chemistry · 2015Article
- Digital sensing and sizing of vesicular stomatitis virus pseudotypes in complex media: a model for Ebola and Marburg detection.ACS nano · 2014Article
- Integrated imaging instrument for self-calibrated fluorescence protein microarrays.The Review of scientific instruments · 2013Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
The use of in vitro diagnostic devices is transitioning from the laboratory to the primary care setting to address early disease detection needs. Time critical viral diagnoses are often made without support due to the experimental time required in today's standard tests. Available rapid point of care (POC) viral tests are less reliable, requiring a follow-on confirmatory test before conclusions can be drawn. The development of a reliable POC viral test for the primary care setting would decrease the time for diagnosis leading to a lower chance of transmission and improve recovery. The single particle interferometric reflectance imaging sensor (SP-IRIS) has been shown to be a sensitive and specific-detection platform in serum and whole blood. This paper presents a step towards a POC viral assay through a SP-IRIS prototype with automated data acquisition and analysis and a simple, easy-to-use software interface. Decreasing operation complexity highlights the potential of SP-IRIS as a sensitive and specific POC diagnostic tool. With the integration of a microfluidic cartridge, this automated instrument will allow an untrained user to run a sample-to-answer viral assay in the POC setting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.