Evidence map›Paper›PMID 24271084›Full record

SynthesisArchives of women's mental health2015

Electroconvulsive therapy during pregnancy: a systematic review of case studies.

Kari Ann Leiknes, Mary Jennifer Cooke, Lindy Jarosch-von Schweder, Ingrid Harboe, Bjørg Høie

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Archives of women's mental health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 4 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 128 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Review
  6. Review
  7. Research Progress in the Treatment of Postpartum Depression.Cellular and molecular neurobiology · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Advancements in Valproate Therapy for Seizures, Migraines, and Bipolar Disorders.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025
    Review
  14. Review
  15. Review
  16. Article
  17. Anesthetic care for electroconvulsive therapy.Anesthesia and pain medicine · 2022
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kari Ann LeiknesNorwegian Knowledge Centre for the Health Services, Box 7004 St. Olavsplass, Pilestredet Park 7, Oslo, 0130, Norway, kle@nokc.no.
Mary Jennifer Cooke
Lindy Jarosch-von Schweder
Ingrid Harboe
Bjørg Høie
Nasjonalt Kunnskapssenter for Helsetjenesten · NOHaukeland University Hospital · NONorwegian University of Science and Technology · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to explore practice, use, and risk of electroconvulsive therapy (ECT) in pregnancy. A systematic search was undertaken in the databases Medline, Embase, PsycINFO, SveMed and CINAHL (EBSCO). Only primary data-based studies reporting ECT undertaken during pregnancy were included. Two reviewers independently checked study titles and abstracts according to inclusion criteria and extracted detailed use, practice, and adverse effects data from full text retrieved articles. Studies and extracted data were sorted according to before and after year 1970, due to changes in ECT administration over time. A total of 67 case reports were included and studies from all continents represented. Altogether, 169 pregnant women were identified, treated during pregnancy with a mean number of 9.4 ECTs, at mean age of 29 years. Most women received ECT during the 2nd trimester and many were Para I. Main diagnostic indication in years 1970 to 2013 was Depression/Bipolar disorder (including psychotic depression). Missing data on fetus/child was 12 %. ECT parameter report was often sparse. Both bilateral and unilateral electrode placement was used and thiopental was the main anesthetic agent. Adverse events such as fetal heart rate reduction, uterine contractions, and premature labor (born between 29 and 37 gestation weeks) were reported for nearly one third (29 %). The overall child mortality rate was 7.1 %. Lethal outcomes for the fetus and/or baby had diverse associations. ECT during pregnancy is advised considered only as last resort treatment under very stringent diagnostic and clinical indications. Updated international guidelines are urgently needed.

Indexed as

Abortion, SpontaneousAdultAnesthetics, GeneralBipolar DisorderElectroconvulsive TherapyFemaleHumansObstetric Labor, PrematurePregnancyPregnancy ComplicationsPregnant PeopleAnesthetics, General

Identifiers

PMID24271084
PMCPMC4305619
OpenAlexW2014379773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.