ArticleNature methods2014
Quantifying RNA allelic ratios by microfluidic multiplex PCR and sequencing.
Article in Nature methods, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed.
- Harnessing RNA base editing for diverse applications in RNA biology and RNA therapeutics.Advanced biotechnology · 2025Review
- ADAR-Mediated A>I(G) RNA Editing in the Genotoxic Drug Response of Breast Cancer.International journal of molecular sciences · 2024Review
- Recommendations for detection, validation, and evaluation of RNA editing events in cardiovascular and neurological/neurodegenerative diseases.Molecular therapy. Nucleic acids · 2024Review
- The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant.EMBO reports · 2023Article
- Article
- MiREDiBase, a manually curated database of validated and putative editing events in microRNAs.Scientific data · 2021Article
- Protein-based molecular recognition tools for detecting and profiling RNA modifications.Current opinion in structural biology · 2021Review
- Direct Immunodetection of Global A-to-I RNA Editing Activity with a Chemiluminescent Bioassay.Angewandte Chemie (International ed. in English) · 2021Article
- Learning cis-regulatory principles of ADAR-based RNA editing from CRISPR-mediated mutagenesis.Nature communications · 2021Article
- Quantitative Analysis of Adenosine-to-Inosine RNA Editing.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Amplified piezoelectrically actuated on-chip flow switching for a rapid and stable microfluidic fluorescence activated cell sorter.RSC advances · 2020Article
- Transcript specific regulation of expression influences susceptibility to multiple sclerosis.European journal of human genetics : EJHG · 2020Article
- Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.Cell reports · 2020Article
- Sense-antisense miRNA pairs constitute an elaborate reciprocal regulatory circuit.Genome research · 2020Article
- A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing.RNA (New York, N.Y.) · 2020Article
- Selective Enrichment of A-to-I Edited Transcripts from Cellular RNA Using Endonuclease V.Journal of the American Chemical Society · 2020Article
- A-to-I RNA Editing in Cancer: From Evaluating the Editing Level to Exploring the Editing Effects.Frontiers in oncology · 2020Review
- Inosine RNA modifications are enriched at the codon wobble position in mouse oocytes and eggs†.Biology of reproduction · 2019Article
- Using mouse models to unlock the secrets of non-synonymous RNA editing.Methods (San Diego, Calif.) · 2019Review
- Single-nucleotide variants in human RNA: RNA editing and beyond.Briefings in functional genomics · 2019Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
We developed a targeted RNA sequencing method that couples microfluidics-based multiplex PCR and deep sequencing (mmPCR-seq) to uniformly and simultaneously amplify up to 960 loci in 48 samples independently of their gene expression levels and to accurately and cost-effectively measure allelic ratios even for low-quantity or low-quality RNA samples. We applied mmPCR-seq to RNA editing and allele-specific expression studies. mmPCR-seq complements RNA-seq for studying allelic variations in the transcriptome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.