Evidence map›Paper›PMID 24270602›Full record

ArticleNature methods2014

A quantitative liposome microarray to systematically characterize protein-lipid interactions.

Antoine-Emmanuel Saliba, Ivana Vonkova, Stefano Ceschia, Greg M Findlay, Kenji Maeda, Christian Tischer, Samy Deghou, Vera van Noort, Peer Bork, Tony Pawson and 2 more

Abstract read
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In one paragraph

Article in Nature methods, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. Exploring lipid-protein interactions in plant membranes.Journal of experimental botany · 2024
    Review
  3. Article
  4. Article
  5. Review
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  8. YPIBP: A repository for phosphoinositide-binding proteins in yeast.Computational and structural biotechnology journal · 2021
    Article
  9. Article
  10. Article
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  13. Article
  14. Article
  15. Article
  16. The Interdependent Activation of Son-of-Sevenless and Ras.Cold Spring Harbor perspectives in medicine · 2019
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Antoine-Emmanuel Saliba1] Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. [2].
Ivana Vonkova1] Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. [2].
Stefano CeschiaStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Greg M FindlaySamuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Kenji MaedaStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Christian TischerAdvanced Light Microscopy Facility, European Molecular Biology Laboratory, Heidelberg, Germany.
Samy DeghouStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Vera van NoortStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Peer BorkStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Tony Pawson1] Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. [2].
Jan EllenbergCell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Anne-Claude GavinStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
European Molecular Biology Laboratory · DEEuropean Molecular Biology Laboratory · DEMount Sinai Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipids have a role in virtually all biological processes, acting as structural elements, scaffolds and signaling molecules, but they are still largely under-represented in known biological networks. Here we describe a liposome microarray-based assay (LiMA), a method that measures protein recruitment to membranes in a quantitative, automated, multiplexed and high-throughput manner.

Indexed as

Microarray AnalysisAutomationEscherichia coliGreen Fluorescent ProteinsHEK293 CellsHumansImage Processing, Computer-AssistedLipidsLiposomesMicroscopy, FluorescenceMutationProtein BindingProteinsRecombinant ProteinsSaccharomyces cerevisiaeSepharoseGreen Fluorescent ProteinsLipidsLiposomesProteinsRecombinant ProteinsSepharose

Identifiers

PMID24270602
OpenAlexW2029164831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.