Evidence map›Paper›PMID 24269987›Full record

ReviewEuropean journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences2014

Microdialysis sampling techniques applied to studies of the foreign body reaction.

Cynthia R Sides, Julie A Stenken

Abstract readReview
In one paragraph

Review in European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Cynthia R SidesDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.
Julie A StenkenDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA. Electronic address: jstenken@uark.edu.

Funding

Quantitative Biocompatibility of Implanted MaterialsR01EB001441 · NIBIB · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI STENKEN, JULIE A · 2003 to 2010
$1.9M
Modulating and Monitoring the Foreign Body Response to ImplantsR01EB014404 · NIBIB · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI STENKEN, JULIE A · 2011 to 2014
$1.3M
NIBIB NIH HHS EB 001441NIBIB NIH HHS EB 014404NIBIB NIH HHS R01 EB001441NIBIB NIH HHS R01 EB014404
6 · The paper itself

Abstract

Implanted materials including drug delivery devices and chemical sensors undergo what is termed the foreign body reaction (FBR). Depending on the device and its intended application, the FBR can have differing consequences. An extensive scientific research effort has been devoted to elucidating the cellular and molecular mechanisms that drive the FBR. Important, yet relatively unexplored, research includes the localized tissue biochemistry and the chemical signaling events that occur throughout the FBR. This review provides an overview of the mechanisms of the FBR, describes how the FBR affects different implanted devices, and illustrates the role that microdialysis sampling can play in further elucidating the chemical communication processes that drive FBR outcomes.

Indexed as

MicrodialysisAnimalsBiomarkersEquipment DesignGranuloma, Foreign-BodyHumansMacrophagesReproducibility of ResultsRisk FactorsTime FactorsBiomarkersCytokinesForeign body reactionMatrix metalloproteinaseMicrodialysis

Identifiers

PMID24269987
PMCPMC4004681

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.