Evidence map›Paper›PMID 24268438›Full record

ReviewSeminars in immunology2013

Functions of the skin microbiota in health and disease.

James A Sanford, Richard L Gallo

Abstract readReview
In one paragraph

Review in Seminars in immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 213 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
213citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

213 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. A systematic review and meta-analysis on Staphylococcus aureus carriage in psoriasis, acne and rosacea.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016
    Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. An Ex Vivo 'Microorganisms · 2026
    Article
  11. Article
  12. Article
  13. Gut and skin microbiota ofFrontiers in microbiology · 2026
    Article
  14. Gut and skin dysbiosis in acne vulgaris: a comparative microbiome analysis.Frontiers in cellular and infection microbiology · 2026
    Article
  15. Review
  16. Microbial community structure in tinea corporis and antifungal activity ofFrontiers in cellular and infection microbiology · 2026
    Article
  17. Review
  18. Review
  19. Article
  20. Article

153 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James A SanfordDivision of Dermatology, Department of Medicine, University of California, San Diego, San Diego, CA, USA.
Richard L Gallo

Funding

UCSD Dermatologist Investigator Training ProgramT32AR062496 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALLO, RICHARD L · 2012 to 2016
$982k
Skin Microbiome in epidermal immune defenseR56AI083358 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALLO, RICHARD L · 2009 to 2009
$123k
NIAID NIH HHS R56 AI083358NIAMS NIH HHS T32 AR062496
6 · The paper itself

Abstract

The skin, the human body's largest organ, is home to a diverse and complex variety of innate and adaptive immune functions. Despite this potent immune system present at the cutaneous barrier, the skin encourages colonization by microorganisms. Characterization these microbial communities has enhanced our knowledge of the ecology of organisms present in normal skin; furthermore, studies have begun to bring to light the intimate relationships shared between host and resident microbes. In particular, it is apparent that just as host immunological factors and behaviors shape the composition of these communities, microbes present on the skin greatly impact the functions of human immunity. Thus, today the skin immune system should be considered a collective mixture of elements from the host and microbes acting in a mutualistic relationship. In this article we will review recent findings of the interactions of skin microbial communities with host immunity, and discuss the role that dysbiosis of these communities plays in diseases of the skin.

Indexed as

AnimalsDysbiosisHumansMicrobiotaSkinAntimicrobial peptidesDysbiosisKeratinocytePropionibacterium acnesStaphylococcus

Identifiers

PMID24268438
PMCPMC4219649

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.