Evidence map›Paper›PMID 24267605›Full record

ReviewClinics in geriatric medicine2014

Anorectal physiology and pathophysiology in the elderly.

Siegfried W B Yu, Satish S C Rao

Abstract readReview
In one paragraph

Review in Clinics in geriatric medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 85 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Psychometric properties of the Arabic IMPACT Bowel Function Short Form for assessing pelvic floor dysfunctions symptoms.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Efficacy of prophylactic laxatives against opioid-induced constipation: retrospective propensity score matching analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  8. Article
  9. Article
  10. Bidirectional Relationships between Sarcopenia and Pelvic Floor Disorders.International journal of environmental research and public health · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Do Age and Sex Influence Anorectal Manometry Parameters?Journal of the Canadian Association of Gastroenterology · 2021
    Article
  18. Fatigability of the external anal sphincter muscles using a novel strength training resistance exercise device.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Siegfried W B YuDivision of Gastroenterology and Hepatology, Medical College of Georgia, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA.
Satish S C Rao
Augusta University · US

Funding

Novel Treatment Strategies for Constipation and Role of Brain-Gut axisR01DK057100 · NIDDK · UNIVERSITY OF IOWA · PI RAO, SATISH SC · 2000 to 2011
$2.7M
NIDDK NIH HHS R01 DK057100NIDDK NIH HHS R01 DK 57100-05NIHRO-1
6 · The paper itself

Abstract

Anorectal medical disorders facing the elderly include fecal incontinence, fecal impaction with overflow fecal incontinence, chronic constipation, dyssynergic defecation, hemorrhoids, anal fissure, and pelvic floor disorders. This article discusses the latest advances in age-related changes in morphology and function of anal sphincter, changes in cellular and molecular biology, alterations in neurotransmitters and reflexes, and their impact on functional changes of the anorectum in the elderly. These biophysiologic changes have implications for the pathophysiology of anorectal disorders. A clear understanding and working knowledge of the functional anatomy and pathophysiology will enable appropriate diagnosis and treatment of these disorders.

Indexed as

AgingAnal CanalColonAgedCellular SenescenceConstipationDefecationDisease ManagementFecal IncontinenceGastrointestinal MotilityHumansNeuromuscular JunctionNeuronal PlasticitySynaptic TransmissionAge-related cellular dysfunctionAnorectal pathophysiologyConstipationElderlyFecal incontinence

Identifiers

PMID24267605
PMCPMC3910254
OpenAlexW2077992674

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.