Evidence map›Paper›PMID 24267514›Full record

ReviewCell communication and signaling : CCS2013

Modulation of host signaling and cellular responses by Chlamydia.

Adrian Mehlitz, Thomas Rudel

Abstract readReview
In one paragraph

Review in Cell communication and signaling : CCS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Journal of bacteriology · 2025
    Review
  4. The N-terminal domain ofFrontiers in immunology · 2025
    Article
  5. Review
  6. Unveiling the stealthy tactics: mycoplasma's immune evasion strategies.Frontiers in cellular and infection microbiology · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Polymorphic Membrane Protein 17G ofFrontiers in immunology · 2021
    Article
  11. Article
  12. Chlamydial Infection From Outside to Inside.Frontiers in microbiology · 2019
    Review
  13. Review
  14. Article
  15. Chlamydia cell biology and pathogenesis.Nature reviews. Microbiology · 2016
    Review
  16. Article
  17. Purification and proteomics of pathogen-modified vacuoles and membranes.Frontiers in cellular and infection microbiology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adrian MehlitzUniversity of Wuerzburg, Biocenter, Department of Microbiology, Am Hubland, D-97074, Wuerzburg, Germany. thomas.rudel@biozentrum.uni-wuerzburg.de.
Thomas Rudel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modulation of host cell signaling and cellular functions is key to intracellular survival of pathogenic bacteria. Intracellular growth has several advantages e.g. escape from the humoral immune response and access to a stable nutrient rich environment. Growth in such a preferred niche comes at the price of an ongoing competition between the bacteria and the host as well as other microbes that compete for the very same host resources. This requires specialization and constant evolution of dedicated systems for adhesion, invasion and accommodation. Interestingly, obligate intracellular bacteria of the order Chlamydiales have evolved an impressive degree of control over several important host cell functions. In this review we summarize how Chlamydia controls its host cell with a special focus on signal transduction and cellular modulation.

Indexed as

Host-Pathogen InteractionsAnimalsBacterial AdhesionBacterial ProteinsChlamydiaChlamydia InfectionsHumansSignal TransductionBacterial Proteins

Identifiers

PMID24267514
PMCPMC4222901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.