ArticleBMC complementary and alternative medicine2013
In vitro anti-mycobacterial activity of nine medicinal plants used by ethnic groups in Sonora, Mexico.
Article in BMC complementary and alternative medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Medicinal Plants in the Treatment of Tuberculosis: A Systematic Review.Central nervous system agents in medicinal chemistry · 2025Pooled it
- Traditional Medicinal Plants as a Source of Antituberculosis Drugs: A System Review.BioMed research international · 2021Pooled it
- Trixis angustifolia DC. as a potential plant for the co-management of diabetes mellitus and tuberculosis.PloS one · 2025Article
- Targeted Screening and Quantification of Characteristic Sesquiterpene Lactones inPlants (Basel, Switzerland) · 2024Article
- Article
- A comprehensive phytochemical and pharmacological review on sesquiterpenes from the genusHeliyon · 2022Review
- Identification and Quantification of Phenolic Compounds from Mexican Oregano (Molecules (Basel, Switzerland) · 2021Article
- A Review on Recent Trends in Green Synthesis of Gold Nanoparticles for Tuberculosis.Advanced pharmaceutical bulletin · 2021Review
- A comprehensive study of the potential phytomedicinal use and toxicity of invasive Tithonia species in South Africa.BMC complementary and alternative medicine · 2018Article
- Southeast Asian Medicinal Plants as a Potential Source of Antituberculosis Agent.Evidence-based complementary and alternative medicine : eCAM · 2017Review
- In vitro antibacterial activity of selected medicinal plants traditionally used in Vietnam against human pathogenic bacteria.BMC complementary and alternative medicine · 2016Article
- Quantitative structure-activity relationship of molecules constituent of different essential oils with antimycobacterial activity against Mycobacterium tuberculosis and Mycobacterium bovis.BMC complementary and alternative medicine · 2015Article
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6 authors.
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Abstract
backgroundSonoran ethnic groups (Yaquis, Mayos, Seris, Guarijíos, Pimas, Kikapúes and Pápagos) use mainly herbal based preparations as their first line of medicinal treatment. Among the plants used are those with anti-tuberculosis properties; however, no formal research is available.
methodsOrganic extracts were obtained from nine medicinal plants traditionally used by Sonoran ethnic groups to treat different kinds of diseases; three of them are mainly used to treat tuberculosis. All of the extracts were tested against Mycobacterium tuberculosis H37Rv using the Alamar Blue redox bioassay.
resultsMethanolic extracts from Ambrosia confertiflora, Ambrosia ambrosioides and Guaiacum coulteri showed minimal inhibitory concentration (MIC) values of 200, 790 and 1000 μg/mL, respectively, whereas no effect was observed with the rest of the methanolic extracts at the concentrations tested. Chloroform, dichloromethane, and ethyl acetate extracts from Ambrosia confertiflora showed a MIC of 90, 120 and 160 μg/mL, respectively.
conclusionsA. confertiflora and A. ambrosioides showed the best anti-mycobacterial activity in vitro. The activity of Guaiacum coulteri is consistent with the traditional use by Sonoran ethnic groups as anti-tuberculosis agent.For these reasons, it is important to investigate a broader spectrum of medicinal plants in order to find compounds active against Mycobacterium tuberculosis.
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